PIKAP study: physicians’ preferences for drug selection and management of pregnant women with bacterial genitourinary infections | CMAC

PIKAP study: physicians’ preferences for drug selection and management of pregnant women with bacterial genitourinary infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2025; 27(2):238-248

​ Bontsevich R.A., Valieva Z.Sh., Puganova O.L., Balamutova T.I., Chukhareva N.A., Tsygankova O.V., Kompaniets O.G., Ketova G.G., Batishcheva G.A., Nevzorova V.A., Martynenko I.M., Pakhomov S.P., Maksimov M.L.
10.36488/cmac.2025.2.238-248
pregnant women genitourinary infections antimicrobials questionnaire physicians’ knowledge level drug safety
Section
Personal Experience
Type
Original Article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2025; 27(2):238-248

Objective.

To analyze physicians’ preferences regarding the pharmacotherapy of bacterial genitourinary infections (UTI) in pregnant women and assess their compliance with current clinical guidelines.

Materials and Methods.

The study was conducted over 2018–2022 using an anonymous questionnaire method among physicians in seven regions of Russia. A total of 227 healthcare providers participated, of whom 66.8% were general practitioners and 33.2% were obstetricians/gynecologists.

Results.

According to the analysis, there is an insufficient level of knowledge in the field of pharmacotherapy of UTIs in pregnant women. The respondents showed the best results in the treatment of chlamydia: in 79.9% of the questionnaires the correct tactics were chosen. The worst results were observed in the issues of detection and treatment of β(beta)-hemolytic streptococcus (BHSV) carriage: in 46.8% and 56.8% of questionnaires, respectively, the wrong tactic was chosen.

Conclusions.

The results of this study showed a low level of knowledge in the field of UTI therapy in different regions, as well as some discrepancies in the issues of pharmacotherapy according to domestic clinical guidelines. The differences are significant in some centers, which may indicate heterogeneity of knowledge in different regions. It is especially important to note that some specialists prescribe antimicrobials characterized by their unsafety for pregnant women and fetus.

Roman A. Bontsevich

Mari State University, Yoshkar-Ola, Russia
Belgorod State National Research University, Belgorod, Russia
Kazan State Medical Academy – branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russia

Valieva Z.Sh.

Kazan State Medical University, Kazan, Russia

Puganova O.L.

Kazan State Medical University, Kazan, Russia

Balamutova T.I.

Medical Center «Promedica», Belgorod, Russia

Chukhareva N.A.

Fomin Clinic, Moscow, Russia

Tsygankova O.V.

Novosibirsk State Medical University, Novosibirsk, Russia
Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia

Kompaniets O.G.

Kuban State Medical University, Krasnodar, Russia

Ketova G.G.

South Ural State Medical University, Chelyabinsk, Russia

Batishcheva G.A.

Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia

Nevzorova V.A.

Pacific State Medical University, Vladivostok, Russia

Martynenko I.M.

Pacific State Medical University, Vladivostok, Russia

Pakhomov S.P.

Kursk State Medical University, Kursk, Russia

Maksimov M.L.

Kazan State Medical Academy – branch of the Russian Medical Academy of Continuous Professional Education, Kazan, Russia
Russian Medical Academy of Continuous Professional Education, Moscow, Russia
N.I. Pirogov Russian National Research Medical University, Moscow, Russia

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