Clinical Microbiology and Antimicrobial Chemotherapy. 2006; 8(2):130-144
Catheter-associated bloodstream infections take a third place among nosocomial infections, and are the most common cause of bacteremia. These infections account for 10% of all infections in hospitalized patients, 20% of nosocomial infections and up to 87% of primary bacteremia. In Europe and USA, >500000 cases of catheter-associated infections occur annually with 80 000 cases are reported in ICU patients. This paper reviews epidemiology, etiology and classification of catheter-associated bloodstream infections, their clinical forms, main diagnostic principles and criteria, and approaches to therapy. Potential for the prophylaxis of these infections is considered in detail.