epidemiology

Objective. To study the prevalence and mechanisms of antibiotic resistance, including carbapenemase production, in clinical isolates of Klebsiella pneumoniae and Escherichia coli isolated in different regions of Russia as part of the sentinel multicenter surveillance study in 2020–2021, and to explore the population structure of K. pneumoniae and the impact of “high-risk clones” on antibiotic resistance. Materials and Methods. Consecutive, non-duplicate isolates of K. pneumoniae (n = 2503) and E.

Mycoplasma pneumoniae is a common etiologic agent of respiratory tract infections and communityacquired pneumonia (CAP) in children and adults. Recently, much new data on this pathogen, its molecular biology, cytoadherence and epidemiology have been …

Objective. To evaluate antimicrobial resistance patterns of clinical Haemophilus influenzae isolates from different regions of Russia during 2014–2017. Materials and Methods. We included in the study 185 clinical H. influenzae isolates from 13 Russian cities. Susceptibility testing was performed by reference broth microdilution method (ISO 207761:2006). Susceptibility testing results were interpreted using EUCAST v. 10.0 breakpoints. Results. H. influenzae isolates were highly susceptible to all (96.8%-100%) β-lactams tested (amoxicillin/ clavulanate, cefixime, ceftaroline, ceftibuten, cefditoren, ertapenem) with the exception of ampicillin (15.

Objective. To estimate the prevalence of S. pneumoniae serotypes in adults aged of 18 years and older, including healthy carriers and patients with acute otitis media (AOM), community-acquired pneumonia (CAP) and invasive pneumococcal infection (IPI). Materials and Methods. A total of 230 isolates of S. pneumoniae from 10 centers were included in the study from 01.06.2019 to 01.10.2019. Re-identification and typing using real-time PCR with 22 primer pairs were performed in the central laboratory (Institute of Antimicrobial Chemotherapy, Russia).

Objective. To evaluate a level of physicians’ awareness of the specific issues of epidemiology, outcomes, prevention and treatment of chronic hepatitis B and C. Materials and Methods. The anonymous questioning was performed among 120 physicians (record of service in a given specialty ranged from 8.1 to 18.6 years) in Kirov city and region. The participants were represented by the following specialties: pediatricians – 41.7% (n=50), obstetricians/gynecologists – 35.8% (n=43), and dentists – 22.

The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological …

Prophylaxis of nosocomial legionellosis is a currently adopted component of the general strategy to fight hospital-acquired infections. In the early 1980s, nosocomial outbreaks of legionnaire disease associated with the high mortality (20 to 40%) …

The susceptibility to aminoglycoside antimicrobials of Gram-negative nosocomial pathogens in Russia and mechanisms of aminoglycoside resistance has been studied. The production of aminoglycoside-modifying enzymes remains to be the major mechanism of …

Nowadays nosocomial infections (NI) remain one of the crucial problems in public health service all over the world. Though antiepidemic actions, the prevalence, mortality rates and NI therapy costs continue to increase. According to the data of …

In spite of the fact that legionellosis is known as a human infectious disease for more than 25 years there is still quite a few difficulties and open problems. At the present article the following topics are described in detail: taxonomy, general …