Personal Experience

Objective. Aim. To evaluate the antimicrobial susceptibility of group A streptococci (GAS) of different emm-genotypes, isolated from patients with invasive and non-invasive skin and soft tissue infections. Materials and Methods. Overall 91 strains of GAS isolated during 2008–2011 from patients with invasive and non-invasive skin and soft tissue infections hospitalized in one Moscow’s hospital were included in the study. Identification was done by latex agglutination, genotyping — by CDC protocol.

This study was performed to investigate activity of chlorhexidine-based antiseptic preparation «Dezin» against the following pathogens causing nosocomial respiratory tract infections (RTI) and urinary tract infections (UTI): Klebsiella pneumoniae …

Using the results from the previous experiments on N-glycans of hepatitis C virus (HCV) glycoprotein E1 in the process of structure viral proteins assembling in the model system (insect cells Sf9 and baculovirus expression system), simulation of …

Objective. To develop and characterize experimental model of chlamydial arthritis in rats. Materials and Methods. Wistar male rats received an intra-articular injection of 0.15–0.20 ml of purified elementary bodies of Chlamydophila (Chlamydia) trachomatis L2/Bu-434 or Chlamydophila (Chlamydia) muridarum Nigg. Animals were divided into two groups: young rats (body weight: 350-380 g) and adult rats (body weight: 450–500 g). Results. No changes in the affected joints were observed in rats infected with C.

Objective. Objectives. In vitro study of biofilm forming capacity of S. aureus and S. epidermidis strains, most common etiological agents of PJI following orthopedic surgeries, depending on source of strain, species of etiological agent and methicillin susceptibility. Materials and Methods. 241 S. aureus and 153 S. epidermidis strains, isolated from the tissue biopsies, the join aspirates and removed orthopedic prosthesis in 2012 year from 321 patients with PJI were investigated.

Staphylococcus aureus is known as the leading pathogen in hospital-acquired infections and the most common cause of skin and soft tissues. The present study aimed to test the genetic background of MSSA isolates obtained from pediatric patients and …

The study of the prevalence of ESBL CTX-M type of nosocomial strains of Enterobacteriaceae was perfomed. CTX-M enzymes have been identified in all ESBLproducing strains of Enterobacteriaceae. Identified β-lactamases belonged to the four genetic …

Currently, treatment of intra-abdominal infections is significantly complicated by increased antimicrobial resistance. Inappropriate antimicrobial therapy is one of the reasons for spread of extended spectrum beta-lactamases (ESBL) both in hospital …

We tested antimicrobial susceptibility of retrospective collection of clinical strains group С and G streptococci (69 strains including 58 strains of Streptococcus dysgalactiae subspecies equisimilis and 11 strains of Streptococcus anginosus). …

This paper considers safety issues associated with medical therapy of sexually transmitted diseases (STDs). Data supporting safety of azithromycin as part of treatment regimens for infections due to chlamydia and mycoplasma are provided. Possible …