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An analysis of all bacteremia cases associated with systemic inflammatory response syndrome among patients hospitalized to City Clinical Hospital named after S.P. Botkin (Moscow) over the 2000–2007 was performed. A total of 303 positive blood culture …

Bacterial vaginosis (BV) is a syndrome characterized by replacement of a normal (resident) vaginal flora with an association of anaerobic microorganisms. The most recently described novel microorganism, Atopobium vaginae, may be involved in …

Objective. Objective: To investigate antagonistic activity of multicomponent probiotic products resulting from interactions of microorganisms; to develop bacterial selection criteria for multi-component biological products. Materials and Methods. Culture fluid of the paired probiotic strain associations: Bifidobacterium longum with Enterococcus faecium («Bifiform» product), Escherichia coli M-17 («Colibacterin» product) and Lactobacillus plantarum 8РА-3 («Lactobacterin» product) were tested for bactericidal activity against Staphylococcus aureus. Also, culture fluid of the each strain was treated with metabolites and peptidoglycan of the associative species and then tested for bactericidal activity against Staphylococcus aureus.

Galenophyllipt is a new natural antiseptic for oral administration and topical use that is similar to commercially available medicinal product Chlorophyllipt. The both products are promising agents for clinical use because of their low toxicity and …

A total of 1375 clinical strains of staphylococci isolated from patients in burn units during the 2002–2008 were tested to detect antimicrobial resistance changes during this period. Antimicrobial susceptibility testing was performed by …

The most common pathogens of skin and soft tissue infections (SSTI) as well as pharmacodynamics parameters of different antimicrobials against S. aureus are considered in this paper. A total of 80 clinical S. aureus isolates obtained from children (0 …

Objective. To investigate the etiology and antimicrobial resistance patterns of aerobic bacterial pathogens in community- and hospital-acquired intra-abdominal infections (IAI) in the ICUs of two teaching hospitals in one particular city. Materials and Methods. A total of 168 patients with peritonitis (122 community-acquired, 46 nosocomial) were included in the study. Susceptibility testing was performed by agar dilution method according to CLSI recommendations. Results. Clinically significant aerobic pathogens were isolated in 61.

Choice of empiric therapy should be based on complex of data on etiology and local antimicrobial resistance trends as well as on clinical-economic analysis. According to our results, from the pharmacoeconomic point of view the most optimal agents for …

This article presents the results of the study to determine etiology and antimicrobial susceptibility in diabetic foot infections (DFI). A total of 288 isolates were obtained from patients with confirmed DFI by fine-needle aspiration/biopsy during …

Community-acquired pneumonia (CAP) remains one of the most common and life-threatening infections. This paper represents a review of laboratory diagnosis of community-acquired pneumonia during the period of 2002– 2006. Local serological and …