Personal Experience

A total of 717 serum samples from haematological patients, who were hospitalized in Botkin City Clinical Hospital (Moscow) in the 2011–2014, were tested. High frequency of hepatitis B virus (HBV) serologic markers was established: HBsAg — 4.5%; …

Objective. To assess potential role of opportunistic microorganisms in the etiology of chronic endometritis by comparison of microbiota of upper and lower genital tract in women of reproductive age with different histopathologic findings of chronic endometritis and endometrial polyps. Materials and Methods. A total of 164 women of reproductive age were enrolled in this study and assigned to four groups by histopathologic changes in endometrium: I — complete set of chronic endometritis findings (n=38); II — partial set of chronic endometritis findings (n=92); III — endometrial polyps (n=15); IV — control group (n=19).

This article presents current view about the mechanisms of human gut microbiota influence on chronic systemic inflammation. Over the last years, evidence of close relationship between different medical conditions and gut microbiota status has been …

Objective. To explore potential of anti-Pseudomonas vaccine for the prophylaxis and treatment of infections caused by Pseudomonas aeruginosa in patients with severe burn trauma. Materials and Methods. This was a pilot, singlecenter randomized, parallel group study which enrolled patients with burns involving 10 to 60% of the body surface area. A total of 24 patients have received a course of «Pseudovac» vaccine (vaccination group), and 24 patients were included in the control arm (non-vaccination group).

The problem of genotypic variety of Acinetobacter baumannii isolated from patients with healthcare associated infections (HCAIs) are discussed. Carbapenemresistant strains, which are predominant in the study region, were shown to belong to the …

Objective. Aim. To evaluate current susceptibility patterns of the potential ocular bacterial pathogens to netilmicin in comparison with other antimicrobials in Russia. Materials and Methods. Overall in the study were included 200 S. aureus strains (100 — MRSA), 50 — coagulase-negative staphylococci, 50 — P. aeruginosa, 50 — Acinetobacter spp., and 50 — Enterobacteriaceae strains, isolated from outpatients and inpatients located in 17 cities of different regions of Russia during 2010–2014.

Relationship between presepsin values and shortterm status of patients with infections, as well as a correlation of presepsin levels and other markers of systemic inflammatory response were analyzed in this prospective observational study. The study …

The results of the immune response intensity and duration in 890 hospital staff after vaccination against hepatitis B are presented. High frequency of HBsAg (1,7%), anti-HBs (21,1%), anti-HВe (16,9%) among not vaccinated against hepatitis B medical …

Objective. Aim. To evaluate the antimicrobial susceptibility of group A streptococci (GAS) of different emm-genotypes, isolated from patients with invasive and non-invasive skin and soft tissue infections. Materials and Methods. Overall 91 strains of GAS isolated during 2008–2011 from patients with invasive and non-invasive skin and soft tissue infections hospitalized in one Moscow’s hospital were included in the study. Identification was done by latex agglutination, genotyping — by CDC protocol.

This study was performed to investigate activity of chlorhexidine-based antiseptic preparation «Dezin» against the following pathogens causing nosocomial respiratory tract infections (RTI) and urinary tract infections (UTI): Klebsiella pneumoniae …