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Personal Experience

Genotyping of Staphylococcus aureus Isolates in Outbreak of Exfoliative Dermatitis in Neonates

Staphylococcus aureus is known as the leading pathogen in hospital-acquired infections and the most common cause of skin and soft tissues. The present study aimed to test the genetic background of MSSA isolates obtained from pediatric patients and …

Characteristics of Enterobacteriaceae Strains Producing CTX-M type ESBL in a Cardiac Surgery Hospital

The study of the prevalence of ESBL CTX-M type of nosocomial strains of Enterobacteriaceae was perfomed. CTX-M enzymes have been identified in all ESBLproducing strains of Enterobacteriaceae. Identified β-lactamases belonged to the four genetic …

Current View on Antimicrobial Therapy of Intra-Abdominal Infections

Currently, treatment of intra-abdominal infections is significantly complicated by increased antimicrobial resistance. Inappropriate antimicrobial therapy is one of the reasons for spread of extended spectrum beta-lactamases (ESBL) both in hospital …

Antimicrobial Resistance of Clinical Isolates of Streptococci Group C and G

We tested antimicrobial susceptibility of retrospective collection of clinical strains group С and G streptococci (69 strains including 58 strains of Streptococcus dysgalactiae subspecies equisimilis and 11 strains of Streptococcus anginosus). …

Efficacy and Safety of Azithromycin in the Treatment of Sexually Transmitted Diseases

This paper considers safety issues associated with medical therapy of sexually transmitted diseases (STDs). Data supporting safety of azithromycin as part of treatment regimens for infections due to chlamydia and mycoplasma are provided. Possible …

Serological Characteristics and Antimicrobial Susceptibility of Streptococcus pneumoniae Isolated from Children Under 5 Years and Patients >65 Years in Belarus and Ukraine

Objective. Objectives. To reveal serotypes of Streptococcus pneumoniaе isolated from patients with pneumococcal infections and from healthy carriers in Belarus and Ukraine. Materials and Methods. There were 314 strains of S. pneumoniae in this investigation, from patients and asymptomatic carriers at the age from 0 to 90 years. After re-identification and susceptibility testing to penicillin, serogroup and serotype was identified for each strain. Using this data the coverage of 7-, 10- and 13-vallent pneumococcal conjugate vaccines was determined.

Characteristics of Nosocomial Strains of Acinetobacter spp. in a Trauma Center

Incidence rates of Acinetobacter spp. isolated from tissue specimens and wound samples in patients with severe burns, chronic osteomyelitis, and diabetic foot infections were determined during the 5 years (2008– 2012). Antimicrobial resistance of …

Lactobacilli Species Diversity in Different States of Vaginal Microbiota in Pregnant Women

Objective. To determine lactobacilli species diversity in different states of vaginal microbiota in pregnant women using culture, mass-spectrometry, and DNAbased assays. Materials and Methods. A total of 163 pregnant women (18 to 40 years of age) were examined in the 2nd or 3rd trimester. A comprehensive microbiological examination of vaginal swabs, including Gram staining, methylene blue staining, and culture was performed. All isolated microorganisms were identified to species level using mass-spectrometry.

SCCmec Typing of Methicillin-Resistant Staphylococcus aureus Strains Isolated from Inpatients and Outpatients in Kazan

Objective. To compare genotypes (by mec complex) of methicillin-resistant S. aureus (MRSA) isolated from different patient populations. Materials and Methods. A total of 191 S. aureus strains were included in the study. These strains were isolated during the period of 2007–2011 from patients examined and treated in a specialized outpatient clinic and patients hospitalized to the Republic Teaching Hospital in Kazan. Susceptibility to oxacillin was determined according to NCCLS standards, and MIC90 for oxacillin was determined according to Guidance 4.

Diagnosis, Treatment Strategy, and Predictors of Septic Complications in Necrotizing Pancreatitis

Analysis of diagnosis and treatment strategies in 25 patients with necrotizing pancreatitis hospitalized to Emergency Care Clinical Hospital (Smolensk) over the period of 2008–2011 is presented in this paper. Rationale for the use of morphologic and …