Diseases and Pathogens | CMAC

Diseases and Pathogens

Clinical case of acute epididymitis in an infant with cytomegalovirus infection

A clinical case of acute epididymitis in a 5-month male infant is presented. Taking into account the occurrence of epididymitis in infancy, an intra-operative biopsy sample was tested for multiple viral pathogens by real-time polymerase chain …

Nontuberculous mycobacteria: modern possibilities of species identification

The paper presents up-to-date review on existing methods of identification of nontuberculous mycobacteria. The advantages and limitations of the use of different identification methods in the real practice in specialized TB laboratories and general …

The role of type III secretion system in the development of nosocomial infections, caused by multiresistant Pseudomonas aeruginosa strains

Type III Secretion System (TTSS) is a key pathogenicity factor of Pseudomonas aeruginosa. The suppression of the activity of TTSS would potentially allow block the infection independently on the presence of antimicrobial resistance. To study the role …

Bacteriophage Preparations and Antibiotic Combinations: In vitro Activity Against Extensively Drug-Resistant Isolates of Pseudomonas aeruginosa ST235

The activity of 11 antibiotics combinations and 4 commercially available preparations for phagotherapy in regard to metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa clinical isolates of sequence type 235 (ST 235) belonging to the clonal …

Perioperative Antibacterial Support to Cataract Surgery

This review contains information on the most common cause of infectious complications of early postoperative cataract surgery, and in particular endophthalmitis, its etiology, the role of the normal microflora in the development of infectious …

New Pathogens in Patients with Cystic Fibrosis: Inquilinus limosus

This paper represents a review of currently available date on potential new pathogen in patients with cystic fibrosis. Chronic microbial colonization of the respiratory tract, leading to exacerbations of pulmonary infection, is the major cause of …

Antimicorbial Susceptibility, Clonal and Serotype Diversity of Streptococcus pneumoniae Isolated from Children with Acute Otitis Media in Moscow

Objective. Streptococcus pneumoniae (pneumococcus) is the leading cause of acute otitis media (AOM) in children. Hereby, we describe antibiotic susceptibility, clonality, and serotype distribution of pneumococci isolated from the middle ear fluid (MEF) in children with AOM. Materials and Methods. MEF specimens from children ≤5 years of age with AOM were collected in 4 pediatric hospitals in Moscow in 2011–2013. Isolation and identification of pneumococcus was performed using standard microbiological procedures.

A Retrospective Data Analysis of the Structure of Isolated Microorganisms in Secondary Skin and Soft Tissue Infections Using Permuted Test

Objective. Objectives. To analyze the structure of microorganisms isolated in patients with secondary skin and soft tissues infection (SSTIs) (trophic ulcers in patients with diabetes mellitus (DM), chronic arterial insufficiency (CAI), chronic venous insufficiency (CVI), pressure sores and to evaluated methodology of data analysis. Materials and Methods. A retrospective analysis of data 2013–2015 and 2006–2007 studies was performed. The structure of isolated microorganisms in patients with DM, CAI, CVI, pressure sores was investigated and multiple comparisons were performed.

Paediatricians Approach to Prescribing of Systemic Antimicrobials in Outpatient Children with Upper Respiratory Tract and ENT Infections: Data from Multicenter Survey

Objective. Objectives. The study aimed to assess paediatricians knowledge of etiology and approach to systemic antimicrobials (АМ) use in outpatient children with acute respiratory tract infections. Materials and Methods. A questionnaire survey of primary care paediatricians from 17 cities of Russian Federation was performed in 2011–2013 in compliance with the unified methodology. Results. A total of 701 paediatricians (mean age 46,3±10,7, 61,5% with work experience >15 years) took part in the survey.

Matrix of Microbial Biofilms

This literature review was aimed to summarize information on an extracellular matrix, which is one of the most important components of microbial biofilms. Structural and biochemical characteristics of biofilms matrix produced by the most common …