Diseases and Pathogens

Mycobacterioses are caused by multiple opportunistic bacteria that are ubiquitous. The incidence rate of nontuberculosis mycobacterial infections (NTM) is rising due to an increased number of immunocompromised patients and advances in diagnosis. …

Objective. The objective of the study was to evaluate the prevalence of Clostridium difficile-associated diarrhea (CDAD) among hospitalized patients with antibiotic-associated diarrhea (AAD) in general and by specific types of medical care and hospital units. Materials and Methods. A prospective, cross-sectional, non-interventional, multicenter study. The main inclusion criteria were: patient age of 18 years and over, hospital stay of at least 48 hours, current antibiotic therapy or antibiotic therapy within the previous 30 days, loose stools (Bristol stool types 5-7 and stool frequency ≥3 within ≤24 consecutive hours or exceeding normal for the patient), and signed informed consent form.

The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological …

Spondylitis is a common disease in general clinical practice, which can be associated with a serious risk of adverse outcomes and severe disabling effects in case of late diagnosis and inadequate management of the patient. This article provides an …

At this prospective 12-months study we investigated the incidence of acute otitis media (AOM), it’s severity and frequency of hospitalization in children from 0 to 5 years old. We detected, that AOM-burden in children under 5-years old in the …

Community-acquired bacterial meningitis is one of the most serious infectious lesions of the central nervous system that can quickly lead to death in even previously healthy patients with inadequate treatment. The article provides an overview of the …

nvasive infections caused by Candida species are the most common invasive fungal infections in children of different age groups. Premature neonates, especially newborns with low and extremely low birth-weight, have very high mortality rates, with the …

A clinical case of acute epididymitis in a 5-month male infant is presented. Taking into account the occurrence of epididymitis in infancy, an intra-operative biopsy sample was tested for multiple viral pathogens by real-time polymerase chain …

The paper presents up-to-date review on existing methods of identification of nontuberculous mycobacteria. The advantages and limitations of the use of different identification methods in the real practice in specialized TB laboratories and general …

Type III Secretion System (TTSS) is a key pathogenicity factor of Pseudomonas aeruginosa. The suppression of the activity of TTSS would potentially allow block the infection independently on the presence of antimicrobial resistance. To study the role …