Biological characteristics and virulence of Helicobacter pylori

Clinical Microbiology and Antimicrobial Chemotherapy. 2018; 20(1):14-23

​ Isaeva G.Sh., Valieva R.I.
10.36488/cmac.2018.1.14-23
Helicobacter pylori pathogenicity factors virulence cytotoxicity adhesion biofilm heterogeneity
Section
Diseases and Pathogens
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2018; 20(1):14-23

Abstract

his review summarizes the most recent data on the biological characteristics of Helicobacter pylori (morphological, cultural, biochemical). H. pylori pathogenicity factors promoting colonization, adhesion, biofilm formation, aggression, and cytotoxicity, their contribution to the pathogenesis of diseases as well as the possible relationships with various clinical outcomes are described in detail. The genetic heterogeneity of H. pylori strains which can determine different clinical manifestations and have significance for conducting epidemiological studies is also considered.

Guzel Sh. Isaeva

Kazan Research Institute of Epidemiology and Microbiology, Kazan, Russia
Kazan State Medical University, Kazan, Russia

Valieva R.I.

Kazan Research Institute of Epidemiology and Microbiology, Kazan, Russia
Kazan State Medical University, Kazan, Russia

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