virulence

Objective. To study genetic determinants of resistance and virulence of K. pneumoniae strains received by the reference center for the prevention of the spread of biological threats of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation. Materials and Methods. The study included 153 strains of Klebsiella pneumoniae isolated from the biological material of pregnant women and newborns in Perinatal centers in various regions of the Russian Federation with infectious and inflammatory diseases and included in the collection of opportunistic microorganisms of the reference center in 2023.

Objective. To analyze and compare multidrug-resistant Klebsiella pneumoniae (KP) strains isolated from different sites of the same patients. Materials and Methods. A total of 30 KP strains isolated from 15 patients treated in intensive care and surgical units in 2020–2021 were studied. Two strains isolated from one child were selected for analyses. One strain was isolated from a clinically significant site (blood/urine/wound/endotracheal aspirate or sputum), the other from a monitoring site (stool).

The rapid expansion of antibiotic-resistant pathogenic bacteria is perceived as a global threat to humanity, which causes significant damage to human health and leads to huge economic losses. Antibiotic resistance is a multifaceted phenomenon, one of …

Objective. To study virulence genes in E. faecium and E. faecalis isolated from the blood cultures of patients with hematological diseases. Materials and Methods. Virulence genes were studied in E. faecium and E. faecalis strains isolated from blood culture from hematological patients in four Russian hospitals (2002–2020). Susceptibility to vancomycin was determined by broth microdilution method (CLSI, 2022). Virulence genes (esp, hyl, asa1, cylA and gelE) in E. faecium and E.

This review provides an analysis of causes why Klebsiella pneumoniae takes a leading place among opportunistic human bacteria. The review includes the history of K. pneumoniae studies, microbiological properties and various Klebsiella-associated …

his review summarizes the most recent data on the biological characteristics of Helicobacter pylori (morphological, cultural, biochemical). H. pylori pathogenicity factors promoting colonization, adhesion, biofilm formation, aggression, and …

Pseudomonas aeruginosa is one of the most important pathogens causing opportunistic infections. This literature review contains analysis of articles on molecular characteristics of P. aeruginosa virulence factors, as well as the pathogenesis of …

Siphoviridae family bacteriophages are known to play a major role in horizontal transfer of virulence genes among Staphylococcus aureus. Integrase group 3 phages transfer genes encoding staphylokinase (sak), staphylococcal complement inhibitor (scn), …