Diseases and Pathogens | CMAC

Diseases and Pathogens

Nosocomial Meningitis

Nosocomial meningitis is one of the life-threatening complications following head injury and neurosurgery interventions. The prevalence of nosocomial meningitis varies widely (0.8% to 17% of the patients undergoing neurosurgery). Nosocomial …

Genetic Characteristics of Neisseria meningitidis Strains in Moscow

This paper provides data on genetic characteristics of circulating Neisseria meningitidis strains in Moscow over the period of 2001–2010. Multilocus sequence typing (MLST) method was used according to international standards. Retrospective analysis …

Encephalitis in Clinical Practice – Is That Simple?

In this review currently available data on the etiological diagnosis, management and treatment of encephalitis are discussed in accordance with the principles of evidence-based medicine. The article represents data in this research field, including …

Efficacy of Intervention Campaign in Outpatients with Acute Tonsillopharyngitis in Smolensk

In this paper the main results of intervention campaign carried out among physicians and patients in different outpatient settings of Smolensk region are presented and discussed. The campaign aimed to improve the practice of antibacterial therapy in …

Diagnosis of Osteomyelitis in Diabetic Foot Syndrome

The risk of the development of diabetic foot syndrome in diabetic patients is more than 25% during the life. Almost half of all cases of diabetic foot syndrome are associated with infections with about 65% of infections involving the bone tissues. At …

Approaches to Diagnosis and Treatment of Acute Male Urethritis: Results of Multicenter Observational Study

Objective. Objectives. To determine the diagnostic and treatment patterns for acute male urethritis (AMU) in Russia. Materials and Methods. Retrospective cross-sectional study was conducted during 2009 in 4 cities of Russia: Kaluga, Pskov, Smolensk and Tula. Data on diagnostic and treatment approaches for AMU subjects ≥16 years old were collected and analyzed using specially designed case report forms. Results. 556 cases of AMU were analyzed during study period. The average age of patients was 29 years (16–68 years).

Empiric Therapy of Invasive Candidiasis in Intensive Care Units: Current State of Problem

The high prevalence of invasive candidiasis (IC) in intensive care units (ICU) is one of the major problems of medical mycology and the modern medicine in general. More than 10% of all infections in ICU are caused by Candida spp. Infections caused by …

Prevention of Legionellosis as a Basis for the New Approach to Prophylaxis of Hospital-Acquired Infections

Prophylaxis of nosocomial legionellosis is a currently adopted component of the general strategy to fight hospital-acquired infections. In the early 1980s, nosocomial outbreaks of legionnaire disease associated with the high mortality (20 to 40%) …

Diagnosis and Management of Bacterial Sexually Transmitted Diseases in Russia: Results of Multicenter Pharmacoepidemiological Study

Objective. Objectives: We aimed to reveal the current practice of diagnosis and management of bacterial sexually transmitted diseases (STDs) in different regions of Russia and to compare it with the current national guidelines. Materials and Methods. A multicenter retrospective study was conducted in 10 different cities of Russia. Randomly selected clinical records of 1250 adult patients (61% male, 39% female, mean age 28.8±9.2) treated for early syphilis (n=341), uncomplicated gonococcal (n=309), chlamydial (n=310), mycoplasma (n=137) and ureaplasma (n=153) infection during the period since January 2007 till December 2007 were analyzed.

Clinical and Laboratory Characteristics of Legionella Pneumonia Depending on Severity of the Disease

Objective. To determine characteristics of community-acquired Legionella pneumonia depending on severity of the disease, identify adverse reactions of long-term antimicrobial regimens, and calculate equation of prognosis of Legionella pneumonia severity upon hospital admission. Materials and Methods. A total of 61 patients with Legionella pneumonia were included and divided into 3 groups depending on the disease severity: Group 1 – 15 patients with non-severe pneumonia without systemic inflammatory response syndrome (SIRS), Group 2 – 32 patients with severe pneumonia and SIRS, Group 3 – 14 patients with very severe pneumonia.