Genetic Characteristics of Neisseria meningitidis Strains in Moscow

Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(2):135-148

Journal article


This paper provides data on genetic characteristics of circulating Neisseria meningitidis strains in Moscow over the period of 2001–2010. Multilocus sequence typing (MLST) method was used according to international standards. Retrospective analysis of genetic characteristics of epidemic serogroup A meningococcal strains isolated during this period was performed. Using the database, our study results were compared to data on circulating strains from other countries. Specific genetic characteristics were identified for circulating Moscow strains. An integrated analysis of genetic and antigenic diversity of epidemic serogroups was also performed. Molecular typing methods were demonstrated to play an important role in microbiologic surveillance for circulating N. meningitidis strains.

0 Abstract
0 Crossref citations