Diseases and Pathogens | CMAC

Diseases and Pathogens

Catheter-Associated Infections in Patients on Hemodialysis

Long-term dialysis therapy in patients with chronic kidney disease is usually associated with vascular access problems, mechanic and infectious complications from the use intravascular devices, and increase in antimicrobial resistance. This paper …

Methodology Issues of Legionella Pneumonia Diagnosis in Medical Institutions

Objective. To determine significance of Legionella pneumonia for hematological patients in ICUs, and to evaluate prospects of the proposed algorithm for diagnosis of legionellosis. Materials and Methods. A total of 37 hematological ICU patients were assessed for legionellosis between December 2010 and February 2012. Bronchoalveolar lavage (BAL) fluid culture and Legionella urinary antigen test (rapid immunochromatographic assay) were used to diagnose legionellosis. Results. Diagnosis of legionellosis was confirmed in 4 (11%) patients, of which 3 had fatal outcome.

Properties of Pseudomonas aeruginosa Strains Causing Nosocomial Infections in Surgical Wards in Federal Scientific Center of Transplantology and Bioartificial Organs

Pseudomonas aeruginosa is the opportunistic microorganism dominating in intensive care units. The present research has been devoted to studying of the causes of long-lasting circulation of certain genotype of P. aeruginosa strains in Federal …

Importance of Appropriate Rapid Diagnosis of C. difficile in Limited Resource Settings

With the ever present threat of healthcare-associated infections such as C. difficile, are we at increased risk of outbreaks whilst resources to decontaminate wards and isolate patients are? Article explores the importance of rapid diagnosis of C. …

Bacterial Biofilms – a New Therapeutic Target?

Biofilms are very specialized but at the same time very widespread form of bacterial existence. Nowadays it is well understood that biofilms play significant role in many human infections. That is way recently a number of research project are …

Methods of Biofilm Evaluation: Opportunities and Perspectives

The review presents the basic approaches to biofilm evaluation. From a methodological point of view, these methods can be divided into two groups: dynamic and static. Each method has advantages and disadvantages discussed in this review. In addition …

Escherichia coli as a Nosocomial Pathogen in ICUs

Over the last years, Gram-negative bacilli are the leading cause of nosocomial infections in different part of the world. Intensive care units (ICUs) differ from other units by continuous healthcare worker-to-patient contacts, large number of …

PCR-based Identification and Serotyping of Russian Streptococcus pneumoniae Strains

The techniques for PCR-based identification and serotyping of Streptococcus pneumoniae were optimized for using in Russian epidemiologic situation. One hundred and thirteen strains isolated from children under 5 years of age in 15 Russian cities were …

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Hospital-Acquired Pneumonia in Patients with Hematological Malignancies in an ICU

Objective. To determine causative agents of hospitalacquired pneumonia (HAP), their incidence rates, and susceptibility to antimicrobial agents in patients with hematological malignancies in an intensive care unit (ICU). Materials and Methods. Broncho-alveolar lavage (BAL) specimens obtained from oncohaematologic patients with pneumonia hospitalized to the ICU between December 2009 and December 2010 were retrospectively studied. Results. A total of 142 BAL specimens were obtained from 72 hospitalized patients aged of 19 to 86 years.