Diseases and Pathogens | CMAC

Diseases and Pathogens

Infections in Russian ICUs: Results of the Nationwide Multicenter Study

Epidemiological data on the prevalence of infections in ICU is crucial for clinical practice. At the same time in Russia only very limited local information was available. So, the aim of the present study was to evaluate the prevalence and etiology …

Hospital-Acquired Pneumonia in Patients with Hematological Malignancies in an ICU

Objective. To determine causative agents of hospitalacquired pneumonia (HAP), their incidence rates, and susceptibility to antimicrobial agents in patients with hematological malignancies in an intensive care unit (ICU). Materials and Methods. Broncho-alveolar lavage (BAL) specimens obtained from oncohaematologic patients with pneumonia hospitalized to the ICU between December 2009 and December 2010 were retrospectively studied. Results. A total of 142 BAL specimens were obtained from 72 hospitalized patients aged of 19 to 86 years.

Current Issues of the Diagnosis of Infections Caused by Group A Streptococci

Currently, culture remains a standard diagnostic method for streptococcal infections. However, over the last decade, rapid diagnostic tests, which are based on direct detection of a streptococcal antigen in tonsil and/or throat swabs, are more …

Basic Principles of the Local Treatment of Wounds and Wound Infection

Due to success in antimicrobial therapy of skin and soft tissue infections, current consensus guidelines give less attention to surgical aspects of wound and wound infection treatment. This paper presents evolution of approaches to treatment of …

Modern Assessment Scores for Severe Community-Acquired Pneumonia: Perspectives and Limitations

Severe pneumonia is associated with high mortality rates, and appropriate severity assessment plays a main role in timely admission to the hospital, including intensive care unit. There are several scores for risk (poor outcome) assessment in …

Contamination of Hot Water Supply Systems with Legionella pneumophila in Public Buildings and Medical Care Institutions

The objective of the study was to determine incidence and level of contamination of hot water supply systems with Legionella pneumophila in public buildings, including medical care institutions, in Moscow region. A total of 12 public buildings or …

Antimicrobial Therapy of Complicated Intra-abdominal Infections: What are the Success Determinants?

Successful outcome of complicated intra-abdominal infections (peritonitis) is determined by two key factors – surgical control of infection site and appropriate and timely antimicrobial therapy. Over the years choice of high antimicrobials for the …

Nosocomial Meningitis

Nosocomial meningitis is one of the life-threatening complications following head injury and neurosurgery interventions. The prevalence of nosocomial meningitis varies widely (0.8% to 17% of the patients undergoing neurosurgery). Nosocomial …

Genetic Characteristics of Neisseria meningitidis Strains in Moscow

This paper provides data on genetic characteristics of circulating Neisseria meningitidis strains in Moscow over the period of 2001–2010. Multilocus sequence typing (MLST) method was used according to international standards. Retrospective analysis …

Encephalitis in Clinical Practice – Is That Simple?

In this review currently available data on the etiological diagnosis, management and treatment of encephalitis are discussed in accordance with the principles of evidence-based medicine. The article represents data in this research field, including …