Aggregatibacter actinomycetemcomitans: Clinical Significance, Diagnosis, Antimicrobial Therapy

Clinical Microbiology and Antimicrobial Chemotherapy. 2012; 14(4):276-279

Journal article


Currently, HACEK group bacteria are a causative agent in 3% of infectious endocarditis cases; of which Aggregatibacter actinomycetemcomitans is the most frequent pathogen. However, this pathogen can be obtained from patients with meningitis, brain abscess, endophthalmitis, skin and soft tissue infections, parotiditis, septic arthritis, osteomyelitis, urinary tract infections, pneumonia, and pericarditis. A. actinomycetemcomitans is a Gram-negative facultative anaerobe, which belongs to Pasteurellaceae family. This paper describes a clinical case of infectious endocarditis caused by A. actinomycetemcomitans. A brief review of currently available data on clinical significance, microbiological diagnosis, and antimicrobial therapy of infections caused by this microorganism is also provided.

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