Diseases and Pathogens | CMAC

Diseases and Pathogens

Diagnosis treatment and prophylaxis of community-acquired bacterial meningitis: the review of the guidelines of European Society for Clinical Microbiology and Infectious Diseases

Community-acquired bacterial meningitis is one of the most serious infectious lesions of the central nervous system that can quickly lead to death in even previously healthy patients with inadequate treatment. The article provides an overview of the …

Review of the guidelines for the treatment and prevention of invasive candidiasis in newborns and children

nvasive infections caused by Candida species are the most common invasive fungal infections in children of different age groups. Premature neonates, especially newborns with low and extremely low birth-weight, have very high mortality rates, with the …

Clinical case of acute epididymitis in an infant with cytomegalovirus infection

A clinical case of acute epididymitis in a 5-month male infant is presented. Taking into account the occurrence of epididymitis in infancy, an intra-operative biopsy sample was tested for multiple viral pathogens by real-time polymerase chain …

Nontuberculous mycobacteria: modern possibilities of species identification

The paper presents up-to-date review on existing methods of identification of nontuberculous mycobacteria. The advantages and limitations of the use of different identification methods in the real practice in specialized TB laboratories and general …

The role of type III secretion system in the development of nosocomial infections, caused by multiresistant Pseudomonas aeruginosa strains

Type III Secretion System (TTSS) is a key pathogenicity factor of Pseudomonas aeruginosa. The suppression of the activity of TTSS would potentially allow block the infection independently on the presence of antimicrobial resistance. To study the role …

Bacteriophage Preparations and Antibiotic Combinations: In vitro Activity Against Extensively Drug-Resistant Isolates of Pseudomonas aeruginosa ST235

The activity of 11 antibiotics combinations and 4 commercially available preparations for phagotherapy in regard to metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa clinical isolates of sequence type 235 (ST 235) belonging to the clonal …

Perioperative Antibacterial Support to Cataract Surgery

This review contains information on the most common cause of infectious complications of early postoperative cataract surgery, and in particular endophthalmitis, its etiology, the role of the normal microflora in the development of infectious …

New Pathogens in Patients with Cystic Fibrosis: Inquilinus limosus

This paper represents a review of currently available date on potential new pathogen in patients with cystic fibrosis. Chronic microbial colonization of the respiratory tract, leading to exacerbations of pulmonary infection, is the major cause of …

Antimicorbial Susceptibility, Clonal and Serotype Diversity of Streptococcus pneumoniae Isolated from Children with Acute Otitis Media in Moscow

Objective. Streptococcus pneumoniae (pneumococcus) is the leading cause of acute otitis media (AOM) in children. Hereby, we describe antibiotic susceptibility, clonality, and serotype distribution of pneumococci isolated from the middle ear fluid (MEF) in children with AOM. Materials and Methods. MEF specimens from children ≤5 years of age with AOM were collected in 4 pediatric hospitals in Moscow in 2011–2013. Isolation and identification of pneumococcus was performed using standard microbiological procedures.

A Retrospective Data Analysis of the Structure of Isolated Microorganisms in Secondary Skin and Soft Tissue Infections Using Permuted Test

Objective. Objectives. To analyze the structure of microorganisms isolated in patients with secondary skin and soft tissues infection (SSTIs) (trophic ulcers in patients with diabetes mellitus (DM), chronic arterial insufficiency (CAI), chronic venous insufficiency (CVI), pressure sores and to evaluated methodology of data analysis. Materials and Methods. A retrospective analysis of data 2013–2015 and 2006–2007 studies was performed. The structure of isolated microorganisms in patients with DM, CAI, CVI, pressure sores was investigated and multiple comparisons were performed.