Diseases and Pathogens

Objective. Streptococcus pneumoniae (pneumococcus) is the leading cause of acute otitis media (AOM) in children. Hereby, we describe antibiotic susceptibility, clonality, and serotype distribution of pneumococci isolated from the middle ear fluid (MEF) in children with AOM. Materials and Methods. MEF specimens from children ≤5 years of age with AOM were collected in 4 pediatric hospitals in Moscow in 2011–2013. Isolation and identification of pneumococcus was performed using standard microbiological procedures.

Objective. Objectives. To analyze the structure of microorganisms isolated in patients with secondary skin and soft tissues infection (SSTIs) (trophic ulcers in patients with diabetes mellitus (DM), chronic arterial insufficiency (CAI), chronic venous insufficiency (CVI), pressure sores and to evaluated methodology of data analysis. Materials and Methods. A retrospective analysis of data 2013–2015 and 2006–2007 studies was performed. The structure of isolated microorganisms in patients with DM, CAI, CVI, pressure sores was investigated and multiple comparisons were performed.

Objective. Objectives. The study aimed to assess paediatricians knowledge of etiology and approach to systemic antimicrobials (АМ) use in outpatient children with acute respiratory tract infections. Materials and Methods. A questionnaire survey of primary care paediatricians from 17 cities of Russian Federation was performed in 2011–2013 in compliance with the unified methodology. Results. A total of 701 paediatricians (mean age 46,3±10,7, 61,5% with work experience >15 years) took part in the survey.

This literature review was aimed to summarize information on an extracellular matrix, which is one of the most important components of microbial biofilms. Structural and biochemical characteristics of biofilms matrix produced by the most common …

Objective. Objectives. Study of the role of herpes viruses and pathogen in the etiology of infectious diseases in children with immunosuppression of different nature to provide an adequate etiotropic therapy and prophylaxis of these infections. Materials and Methods. We examined 30 children with immunosuppression due to congenital HIV infection and 30 children receiving immunosuppressive drug therapy after liver transplantation. Results. Identified a high prevalence of markers of GWI and pneumocystosis in children with immunosuppression of various etiologies.

Septic arthritis is a rheumatologic emergency as joint destruction occurs rapidly and can lead to significant morbidity and mortality. The risk of septic arthritis significantly increased in patients with premorbid affected joints (especially with …

Pseudomonas aeruginosa is one of the most important pathogens causing opportunistic infections. This literature review contains analysis of articles on molecular characteristics of P. aeruginosa virulence factors, as well as the pathogenesis of …

The article presents the current classification of herpesviruses, clinical features of infections caused by β-herpesviruses, as well as methods of laboratory diagnosis and treatment of these infections.

Objective. To investigate etiology of infective endocarditis in Russian Federation. Materials and Methods. Multicenter prospective (September 2011 to December 2013) and retrospective (January 2006 – September 2011) studies to investigate etiology of infective endocarditis (IE) were performed at medical institutions in 10 Russian cities. Patients with definite or possible diagnosis of IE who have at least 1 blood culture collected were enrolled in the study. Results. A total of 401 patients with IE were included in the analysis: 161 (40.