Antimicrobials

Infectious complications of pancreatic cysts (PC) is one of the problem of modern medicine due to insufficient data on pharmacokinetic of majority of antimicrobials resulting to the lack of standards for antimicrobial therapy and prophylaxis of this …

This article presents data of multicenter open-label randomized clinical trial of clinical and microbiological efficacy and safety of 7- and 10-day courses of new formulation («Solutab») of josamycin in the treatment of acute streptococcal …

There are many antibiotics from various chemical classes available in drug armamentarium for the treatment of community-acquired infections at out-patient basis. In such cases safety and tolerability of administered treatment is of no less importance …

Surgical site infections (SSI) currently remain a significant medical problem due to their high incidence, severity, social consequences, and healthcare costs. An advanced approach to prevent SSI which considers surgical suture material as an implant …

Aminoglycosides is one of the main antimicrobial drug classes and continue to play a role in the treatment of several infections, although their relatively high rate of specific adverse reactions. Tobramycin is a typical antibiotic of this class …

Generic drugs account for 78 to 95% of drug products on the Russian pharmaceutical market and represent a common way of decreasing treatment cost. The main problem of generic drugs is a pharmaceutical quality and comparability between generic and …

Daptomycin is the first approved member of a cyclic lipopeptides class of antibiotics with anti-Gram(+) activity. In contrast to majority of other antimicrobials daptomycin has rapid bactericidal activity against not only rapidly growing, but also …

Collateral damage concept describes an adverse ecological effect associated with the use of antimicrobial agents. The main point is a selection of multidrug-resistant strains and subsequent colonization and infections caused by those microorganisms. …

Ciprofloxacin is the most known member of second generation quinolones, which is more active against gram-negative microorganisms and has broad antimicrobial spectrum compared to first generation quinolones. This article presents the main indications …

Beta-lactams remain one of the most commonly used antimicrobial classes in the treatment of community-acquired respiratory tract infections worldwide. Among them, cephalosporins take one of the main places because of their broad spectrum of activity …