Острая печеночная недостаточность в практике инфекционистов и врачей смежных специальностей: обновленные подходы к ведению пациентов

Светлана Петровна Лукашик; Игорь Александрович Карпов

doi:10.36488/cmac.2025.2.150-166

Острая печеночная недостаточность в практике инфекционистов и врачей смежных специальностей: обновленные подходы к ведению пациентов

Клиническая микробиология и антимикробная химиотерапия. 2025; 27(2):150-166

Лукашик С.П., Карпов И.А.

10.36488/cmac.2025.2.150-166

острая печеночная недостаточность этиология диагностика лечение трансплантация печени

Раздел

Болезни и возбудители

Тип

Обзор

Публикация

Клиническая микробиология и антимикробная химиотерапия. 2025; 27(2):150-166

Аннотация Авторы Литература PDF Статистика Репринты

Аннотация

Острая печеночная недостаточность (ОПН) – быстро развивающееся состояние с разнообразными этиологическими факторами и не до конца изученными механизмами патогенеза. Решающее значение для прогноза пациентов с ОПН имеют своевременное установление ее причины и быстрое начало этиотропного лечения, выявление, профилактика и лечение осложнений, а также часто – ранняя трансплантация печени (ТП). Современные прогностические модели для выявления пациентов с ОПН, которые нуждаются в экстренной ТП, обладают хорошей точностью, но требуют усовершенствования. Новые прогностические маркеры для отбора пациентов для ТП все еще находятся в стадии разработки. В обзоре основное внимание уделено практическим клиническим аспектам и последним достижениям в диагностике и лечении ОПН.

Лукашик Светлана Петровна

Svetlanalukashik@mail.ru

УО «Белорусский государственный медицинский университет», Минск, Республика Беларусь

Карпов Игорь Александрович

УО «Белорусский государственный медицинский университет», Минск, Республика Беларусь

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