Умеренные бактериофаги энтерококков: генетические особенности и практическое применение | КМАХ

Умеренные бактериофаги энтерококков: генетические особенности и практическое применение

Клиническая микробиология и антимикробная химиотерапия. 2022; 24(3):213-218

​ Ткачев П.В., Гончаров А.Е., Дмитриев А.В.
10.36488/cmac.2022.3.213-218
Enterococcus spp умеренные бактериофаги антибиотикорезистентность фаготерапия биотехнология
Раздел
Болезни и возбудители
Тип
Обзор
Публикация
Клиническая микробиология и антимикробная химиотерапия. 2022; 24(3):213-218

Аннотация

Умеренные бактериофаги представляют интерес в качестве носителей и векторов факторов патогенности, определяющих эпидемический потенциал условно-патогенных бактерий, а также в качестве объектов биотехнологии. В данном обзоре представлена ретроспектива исследований умеренных бактериофагов, инфицирующих бактерии рода Enterococcus, включая штаммы, обуславливающие развитие нозокомиальных инфекций. Рассмотрены генетические особенности умеренных энтерококковых бактериофагов, а также описываются варианты их потенциального практического применения в медицине – как уже используемые, так и разрабатываемые.

Павел Владимирович Ткачев

ФГБНУ «Институт экспериментальной медицины», Санкт-Петербург, Россия

Гончаров А.Е.

ФГБНУ «Институт экспериментальной медицины», Санкт-Петербург, Россия

Дмитриев А.В.

ФГБНУ «Институт экспериментальной медицины», Санкт-Петербург, Россия

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