Применение хлоргексидина для профилактики госпитальных инфекций в отделениях реанимации и интенсивной терапии: современное состояние проблемы | КМАХ

Применение хлоргексидина для профилактики госпитальных инфекций в отделениях реанимации и интенсивной терапии: современное состояние проблемы

Клиническая микробиология и антимикробная химиотерапия. 2020; 22(1):30-38

​ Багин В.А., Руднов В.А., Астафьева М.Н.
10.36488/cmac.2020.1.30-38
хлоргексидин госпитальные инфекции нозокомиальные инфекции отделение реанимации и интенсивной терапии ОРИТ
Раздел
Антимикробные препараты
Тип
Обзор
Публикация
Клиническая микробиология и антимикробная химиотерапия. 2020; 22(1):30-38

Аннотация

В статье приведен анализ литературных данных об использовании различных форм хлоргексидина для профилактики госпитальных инфекций в отделении реанимации и интенсивной терапии (ОРИТ). Использование 0,5–2,0% спиртового раствора хлоргексидина строго рекомендовано в качестве препарата первой линии для обработки операционного поля перед хирургической операцией или пункцией сосуда для снижения риска инфекций в области хирургического вмешательства и катетер-ассоциированных инфекций кровотока (КАИК). Следует рассмотреть возможность следующих мероприятий: ежедневная обработка кожи пациентов ОРИТ водным раствором хлоргексидина для снижения риска КАИК; использование повязок для сосудистых катетеров, импрегнированных хлоргексидином для снижения риска КАИК и колонизации катетера; обработка наружного отверстия мочеиспускательного канала водным раствором хлоргексидина для профилактики катетер-ассоциированных инфекций мочевых путей. Не оправданно рутинное использование хлоргексидина для обработки полости рта для профилактики вентилятор-ассоциированной пневмонии. Во всех случаях использования хлоргексидина следует учитывать вероятность развития контактного дерматита, анафилаксии и возможность появления резистентных к нему штаммов микроорганизмов.

Багин Владимир Анатольевич

Городская клиническая больница №40, Екатеринбург, Россия
ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России, Екатеринбург, Россия

Руднов Владимир Александрович

Городская клиническая больница №40, Екатеринбург, Россия
ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России, Екатеринбург, Россия

Астафьева Мария Николаевна

Городская клиническая больница №40, Екатеринбург, Россия
ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России, Екатеринбург, Россия

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