Аннотация
Несмотря на появление новых классов антибактериальных препаратов, аминогликозидные антибиотики по-прежнему широко используются в клинической практике. Бактерицидное действие в отношении многих микроорганизмов, синергизм при сочетании с другими антибиотиками позволяют использовать этот класс антибактериальных препаратов для лечения нозокомиальных, в том числе тяжёлых, а также некоторых внебольничных инфекций. В данной статье представлен обзор данных по одному из наиболее интересных представителей аминогликозидов — нетилмицину. Подробно рассмотрены основные аспекты фармакокинетики, фармакодинамики и особенности клинического применения в сравнении с другими антимикробными препаратами. Большое внимание уделено обсуждению проблем антибиотикорезстентности к различным аминогликозидам в России и других странах.
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