Резистентность шигелл и современные возможности антибактериальной терапии шигеллёзов | КМАХ

Резистентность шигелл и современные возможности антибактериальной терапии шигеллёзов

Клиническая Микробиология и Антимикробная Химиотерапия. 2005; 7(4):350-368

​ Малеев В.В., Иванов А.С., Страчунский Л.С.
шигеллёз Shigella spp антибиотикорезистентность антибактериальная терапия
Раздел
Антибиотикорезистентность
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2005; 7(4):350-368

Аннотация

Многообразие механизмов резистентности, обнаруживаемых у шигелл, и свободный обмен генами резистентности не только в пределах рода, но и внутри семейства Enterobacteriaceae вызывают большие трудности при выборе адекватной антибактериальной терапии шигеллёзов. Активность большинства традиционно применявшихся для терапии шигеллёзов антибиотиков, таких как ампициллин, ко-тримоксазол и тетрациклины, в настоящее время значительно снизилась. В обзоре подробно рассматривается возможность применения различных классов антимикробных препаратов для лечения шигеллёзов у взрослых и детей на основе доказательных данных по эффективности и безопасности.

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