Микробиологическая характеристика возбудителя коклюша и лабораторная диагностика коклюша

Клиническая Микробиология и Антимикробная Химиотерапия. 2003; 5(4):329-341

​ Ценева Г.Я., Курова Н.Н.
коклюш Bordetella pertussis факторы патогенности коклюшный токсин лабораторная диагностика
Раздел
Болезни и возбудители
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2003; 5(4):329-341

Аннотация

Коклюш остается актуальной инфекцией во всем мире, в том числе в странах с высоким уровнем иммунизации населения. В то же время до сих пор отсутствуют специфичные, высокочувствительные и легко воспроизводимые методы диагностики этой инфекции, которые бы удовлетворяли потребностям практического здравоохранения. В 1980-90-е годы были получены новые данные об антигенной структуре Bordetella pertussis и факторах патогенности этого микроорганизма. Представлен обзор данных по микробиологической характеристике возбудителя коклюша и родственных ему бактерий. Описаны различные факторы патогенности B.pertussis, их роль в развитии заболевания и формировании иммунитета у человека. Рассмотрены некоторые вопросы патогенеза коклюша. Описываются различные методы лабораторной диагностики инфекции, вызванной B.pertussis, их преимущества и недостатки.

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