Аннотация
Лечение интраабдоминальных инфекций (ИАИ) по-прежнему остается актуальной проблемой хирургии. В настоящей статье представлен анализ рекомендаций по антимикробной терапии ИАИ, опубликованных в конце 2002 г. Североамериканским обществом по хирургическим инфекциям, с учётом особенностей клинической практики в России. Рассмотрены такие принципиальные вопросы терапии ИАИ, как категории пациентов, которым необходимы антибактериальная терапия и определение её оптимальной продолжительности. Представлены основные режимы антибиотикотерапии, обладающие по результатам большого количества проспективных контролируемых исследований высокой клинической эффективностью. Установлены факторы риска неэффективности терапии и развития летального исхода у пациентов с ИАИ. Показаны особенности выбора антимикробной терапии у этой категории больных, определены основные направления для будущих исследований в области совершенствования антибактериальной терапии ИАИ.
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