therapy

Antibacterial agents reducing the risk of resistance development

The most important goal of medical microbiology in terms of treating infectious diseases nowadays and in the coming decades will be the development of antibacterial agents that are effective against resistant pathogens and reduce the selection of …

Bacteriophage therapy: back to the future

In connection with growing problem of antimicrobial resistance, the search for alternative treatments for infection is popular topic nowadays. This article represents an overview of published data on the therapeutic use of bacteriophages, …

War and Peace: the difficult treatment of urinary tract infections and fosfomycin trometamol

The title of this review “War and peace” is not accidental and the analogies with a well-known literary masterpiece have absolutely justified ground. As in the case of Lev Tolstoy’s novel this title has a profound philosophical meaning, although at …

Complicated Community-Acquired Urinary Tract Infections in Adult Patients in Russia

Objective. Objectives. To analyze etiology and antimicrobial resistance of pathogens causing complicated community-acquired urinary tract infections (cUTI) in adult patients in different regions of Russia. Materials and Methods. Uropathogens isolated from urine samples of patients of both gender older than 18 years of age with community-acquired UTI were collected in 21 centers of 17 cities in Russia during 2010–2011 and included in the «DARMIS» study. Results. Among the collected 518 strains isolated from adult patients 282 strains (54,4%) were isolated from urine of patients with cUTI.

Treatment of Acute Tonsillitis/Pharyngitis: Current Guidelines and Russian Local Situation

The article analyzes contemporary recommendations for diagnosis and treatment of acute tonsillopharyngitis, and essential practical aspects for management of patients with this infection considering characteristics of antibiotic resistance profile of …

Antibacterial Therapy of Infectious Exacerbations of Chronic Bronchitis: from Pathogen Eradication to Long-Term Relapse-Free Period

Chronic obstructive pulmonary disease (COPD) is a chronic illness that is characterized by recurring exacerbations. Exacerbations lead to the progression of the disease with development of respiratory failure, decreasing of the quality of life of the …

Rhodococcus spp.: Clinical Importance, Diagnosis and Antimicrobial Therapy

The clinical significance of nocardioform bacteria isolated recently in a distinct genus Rhodococcus, as pathogens of infectious diseases in human also has not been sufficiently studied and specified. In the literature there are described a slightly …

Encephalitis in Clinical Practice – Is That Simple?

In this review currently available data on the etiological diagnosis, management and treatment of encephalitis are discussed in accordance with the principles of evidence-based medicine. The article represents data in this research field, including …