Helicobacter pylori

Pharmacoepidemiology of peptic ulcer in Smolensk: 15 years later

Objective. To study management of patients with peptic ulcer based on outpatient card data and to evaluate changes in methods for diagnosis of H. pylori and treatment prescriptions compared with 2004– 2005. Materials and Methods. A total of 100 outpatient cards of patients aged 18 years and older who came to outpatient clinic visit for peptic ulcer over the period of 2015–2018 were analyzed. The results of this study were compared with the data from the pharmacoepidemiological study «Ulcer», which was performed in 2004–2005 in Smolensk.

Comparison of in vitro activity of various macrolides against Helicobacter pylori

Objective. Compare the in vitro activity of clarithromycin, erythromycin, azithromycin and josamycin against the collection of H. pylori strains isolated in 2010–2017 in Smolensk. Materials and Methods. H. pylori strains were collected prospectively from biopsy specimens of the gastric mucosa. Antimicrobial susceptibility testing of H. pylori was performed by the agar dilution method. Interpretation of the results of the susceptibility determination for clarithromycin was carried out in accordance with the recommendations of EUCAST (v 8.

Antimicrobial resistance of Helicobacter pylori in Smolensk

Objective. To study the antimicrobial resistance of H. pylori to clarithromycin, amoxicillin, metronidazole, levofloxacin, tetracycline in adult patients in the Smolensk region. Materials and Methods. Overall, 573 adult patients were included in 2015-2017 and 210 – in 20092010 with positive rapid urease test at the time of gastroscopy for dyspeptic complaints. Antimicrobial susceptibility testing of H. pylori isolates to clarithromycin, amoxicillin, metronidazole, levofloxacin and tetracycline was performed by the agar dilution method.

Biological characteristics and virulence of Helicobacter pylori

his review summarizes the most recent data on the biological characteristics of Helicobacter pylori (morphological, cultural, biochemical). H. pylori pathogenicity factors promoting colonization, adhesion, biofilm formation, aggression, and …

Antimicrobial Susceptibility of Helicobacter pylori Isolates from Patients with Gastric Cancer and Precancer

colonization of gastric mucosa with Helicobacter pylori in patients with precancerous conditions (adenomatous polyp, hyperplastic polyp, focal hypertrophy, erosions) and gastric cancer (adenocarcinoma, signet ring cell carcinoma, carcinoid). The …

Role of Helicobacter pylori in Human Pathology

Helicobacter pylori is one of the most common pathogens in humans. H.pylori associated gastric diseases include chronic gastritis, gastric and duodenal peptic ulcer; moreover, role of this microorganism as a causative factor in the development of …