antimicrobial resistance

We studied 126 children, admitted to cardiac surgery hospital with colonization of the gastrointestinal tract (GIT) by multidrug-resistant Enterobacteriaceae. Criterion for inclusion in the study were children with complex congenital heart disease …

This paper presents the results of a microbiological study of clinical specimens obtained from 64 patients with chronic post-traumatic osteomyelitis of long bones during the 2011–2013. A total of 136 clinical strains were isolated and identified to a …

Objective. Aim. To evaluate current susceptibility patterns of the potential ocular bacterial pathogens to netilmicin in comparison with other antimicrobials in Russia. Materials and Methods. Overall in the study were included 200 S. aureus strains (100 — MRSA), 50 — coagulase-negative staphylococci, 50 — P. aeruginosa, 50 — Acinetobacter spp., and 50 — Enterobacteriaceae strains, isolated from outpatients and inpatients located in 17 cities of different regions of Russia during 2010–2014.

Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods. This was a multicenter (a total of 21 cities), prospective, microbiological study to collect Gram-negative pathogens from patients with complicated IAI. Identification was performed using MALDITOF mass spectrometry. Minimal inhibitory concentrations (MICs) of antibiotics were determined by dilution method according to the current CLSI and EUCAST guidelines. Results. A total of 1908 isolates of gram-negative pathogens was obtained (357 isolates in community-acquired IAI, and 1551 isolates in nosocomial IAI).

Objective. Aim. To evaluate the antimicrobial susceptibility of group A streptococci (GAS) of different emm-genotypes, isolated from patients with invasive and non-invasive skin and soft tissue infections. Materials and Methods. Overall 91 strains of GAS isolated during 2008–2011 from patients with invasive and non-invasive skin and soft tissue infections hospitalized in one Moscow’s hospital were included in the study. Identification was done by latex agglutination, genotyping — by CDC protocol.

One of the main mechanisms of resistance of Gramnegative microorganisms to antibiotics is enzymatic hydrolysis by beta-lactamases (for example, metallobeta-lactamases). Searching of paths of strengthening of carbapenems action is possible due to …

Objective. To investigate etiology of infective endocarditis in Russian Federation. Materials and Methods. Multicenter prospective (September 2011 to December 2013) and retrospective (January 2006 – September 2011) studies to investigate etiology of infective endocarditis (IE) were performed at medical institutions in 10 Russian cities. Patients with definite or possible diagnosis of IE who have at least 1 blood culture collected were enrolled in the study. Results. A total of 401 patients with IE were included in the analysis: 161 (40.

In total 284 clinical nosocomial S. aureus strains isolated in 2011–2012 from patients hospitalized in 25 hospitals in 18 Russian cities were included in the study. Susceptibility to 19 antimicrobials was assessed by serial dilution method in …

Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 343 isolates of P. aeruginosa collected in 25 hospitals of 18 cities of Russia …

Acinetobacter baumannii and related species of the Acinetobacter calcoaceticus-baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 252 …