antimicrobial resistance | CMAC

antimicrobial resistance

Antimicrobial Susceptibility of Helicobacter pylori Isolates from Patients with Gastric Cancer and Precancer

colonization of gastric mucosa with Helicobacter pylori in patients with precancerous conditions (adenomatous polyp, hyperplastic polyp, focal hypertrophy, erosions) and gastric cancer (adenocarcinoma, signet ring cell carcinoma, carcinoid). The …

Current Trends in Antimicrobial Resistance of Neisseria gonorrhoeae in Russian Federation

Objective. of current Neisseria gonorrhoeae isolates and determine its trends over the RU-GASP (Russian Gonococcal Antimicrobial Susceptibility Programme) period. Materials and Methods. A total of 293 strains of N. gonorrhoeae isolated in 11 regions within Central, North-Western, Volga, Southern, and Siberian federal districts over the 2015–2016 were included in this study. Susceptibility to benzylpenicillin, ceftriaxone, tetracycline, spectinomycin, azithromycin, and ciprofloxacin was determined by agar dilution method and assessed according to the CLSI, EUCAST and MUK 4.

Prognostic Model of Microbial Resistance Based on the Relationship between Antibiotic Resistance and Consumption

Acquired bacterial resistance is one of the leading causes of morbidity and mortality attributed to infectious diseases. Simulations may provide opportunity to predict further spread of resistance and, to some extent, manage it. The objective of this …

Production of Carbapenemases in Klebsiella pneumoniae Isolated in Saint-Petersburg

Carbapenem-resistant nosocomial K. pneumoniae isolates are a significant problem in clinical practice. Carbapenem resistance in K. pneumoniae isolated from hospitalized patients was 2.8% over the study period. NDM-1 carbapenemase-producing strains …

Responsible Use of Antibiotics in Food Animals

Antimicrobial use in food animal medicine has become an important political and scientific issue, especially in relation to the contribution that animal sourced antimicrobial resistance might play in human medicine, leading to calls at a political …

Primary Antimicrobial Resistance among Helicobacter pylori Isolated in the Republic of Tatarstan in the 2008–2013

This study was aimed to determine isolation rate of H. pylori from gastric mucosal biopsies in 869 patients with chronic gastritis and gastric peptic ulcers in Republic of Tatarstan during the 2008–2013. A total of 45.5% of gastric biopsy samples …

Multidrug-Resistant Enterobacteriaceae Colonizing Gastrointestinal Tract in Infants with Congenital Heart Disease on Admission to Cardiac Surgery Hospital

We studied 126 children, admitted to cardiac surgery hospital with colonization of the gastrointestinal tract (GIT) by multidrug-resistant Enterobacteriaceae. Criterion for inclusion in the study were children with complex congenital heart disease …

Antimicrobial Resistance of Microorganisms Causing Chronic Post-Traumatic Osteomyelitis

This paper presents the results of a microbiological study of clinical specimens obtained from 64 patients with chronic post-traumatic osteomyelitis of long bones during the 2011–2013. A total of 136 clinical strains were isolated and identified to a …

Surveillance of Activity of Netilmicin in Comparison with Other Antimicrobials against Russian Ophtalmic Bacterial Isolates

Objective. Aim. To evaluate current susceptibility patterns of the potential ocular bacterial pathogens to netilmicin in comparison with other antimicrobials in Russia. Materials and Methods. Overall in the study were included 200 S. aureus strains (100 — MRSA), 50 — coagulase-negative staphylococci, 50 — P. aeruginosa, 50 — Acinetobacter spp., and 50 — Enterobacteriaceae strains, isolated from outpatients and inpatients located in 17 cities of different regions of Russia during 2010–2014.

Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia

Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods. This was a multicenter (a total of 21 cities), prospective, microbiological study to collect Gram-negative pathogens from patients with complicated IAI. Identification was performed using MALDITOF mass spectrometry. Minimal inhibitory concentrations (MICs) of antibiotics were determined by dilution method according to the current CLSI and EUCAST guidelines. Results. A total of 1908 isolates of gram-negative pathogens was obtained (357 isolates in community-acquired IAI, and 1551 isolates in nosocomial IAI).