Antimicrobial resistance – are we aware of all the sources?

Clinical Microbiology and Antimicrobial Chemotherapy. 2025; 27(2):229-237

Zakharova E.A., Lyamin A.V., Sustretov A.S., Kayumov K.A., Alekseev D.V., Platonov V.I., Orlova L.V.

10.36488/cmac.2025.2.229-237

antimicrobial resistance agriculture One Health

Section

Antimicrobial Resistance

Type

Review

Publication

Clinical Microbiology and Antimicrobial Chemotherapy. 2025; 27(2):229-237

Abstract Authors Literature PDF Statistics

Abstract

The problem of antimicrobial resistance represents one of the most urgent and complex problems of modern healthcare. The measures that are being taken today to control antimicrobial resistance, however, cannot be considered satisfactory, and we are seeing an increasing prevalence of antibiotic-resistant microorganisms worldwide. One of the reasons for this may be the uncontrolled use of antimicrobials in the areas not connected with the healthcare, in particular in agriculture. In the last few decades, there has been an active discussion on the unjustified use of antimicrobials in animal husbandry and veterinary medicine, but the potential pool of antibiotic-resistant strains in soils, including agricultural land, has been virtually ignored, though it is the main source of food for humans and, therefore, a potential pathway for the transmission of antibiotic resistance factors. The article discusses the main possible pathways of formation of resistant strains in soils and their clinical relevance within the framework of the concept of ‘One Health’.

Elena A. Zakharova

e.a.zakharova@samsmu.ru

Professional Center for Education and Research in Genetic and Laboratory Technologies, Samara State Medical University, Samara, Russia

Artem V. Lyamin

Professional Center for Education and Research in Genetic and Laboratory Technologies, Samara State Medical University, Samara, Russia

Sustretov A.S.

Professional Center for Education and Research in Genetic and Laboratory Technologies, Samara State Medical University, Samara, Russia

Kayumov K.A.

Professional Center for Education and Research in Genetic and Laboratory Technologies, Samara State Medical University, Samara, Russia

Dmitriy V. Alekseev

Professional Center for Education and Research in Genetic and Laboratory Technologies, Samara State Medical University, Samara, Russia

Platonov V.I.

Samara National Research University named after S.P. Korolev, Samara, Russia

Orlova L.V.

National Movement for Resource-Saving Agriculture in Russia, Samara, Russia

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