Comparative analysis of antimicrobial resistance monitoring methodologies at the local healthcare level

Abstract

Despite ongoing efforts by various countries to combat antimicrobial resistance (AMR), the problem remains a global-scale threat, particularly in the context of nosocomial infections, where resistant pathogens are associated with high mortality. Global (GLASS) and national (AMRmap) AMR monitoring systems provide valuable population-level data; however, for clinical decision-making at the individual patient level, highquality local epidemiological data enabling optimization of empirical antimicrobial therapy is critically important. In practice, the collection and use of local data in the Russian Federation are limited, particularly by the lack of methodological standards and low availability of digital tools. This review conducts a comparative analysis of key international and Russian guidelines for organizing AMR monitoring to assess their applicability for addressing local monitoring tasks in healthcare facilities and to identify similarities and contradictions in their approaches.