Clinical and microbiological characteristics of periprosthetic hip and knee infections | CMAC

Clinical and microbiological characteristics of periprosthetic hip and knee infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2020; 22(3):237-240

​ Ivantsov V.A., Bogdanovich I.P., Lashkovskiy V.V., Anosov V.S.
10.36488/cmac.2020.3.237-240
periprosthetic joint infection total joint replacement surgical treatment
Section
Personal Experience
Type
Original Article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2020; 22(3):237-240

Objective.

To characterize periprosthetic joint infection in patients undergoing a total hip and knee joint replacement.

Materials and Methods.

A total of 77 patients with periprosthetic infection following hip and knee joint replacement hospitalized in Grodno City Clinical Hospital were studied over the period of 2014-2018. Wound discharge, tissue samples, and fistula’s wall swab were used for microbiological tests. The analysis of surgical treatment of patients with deep periprosthetic knee and hip joint infection has been performed.

Results.

Periprosthetic infection after hip joint arthroplasty was observed in 32 (41.6%) patients, and after total knee joint arthroplasty in 45 (58.4%) patients. Surgical treatment was performed in 18 (56.3%) and 32 (71.1%) patients with periprosthetic infection following total knee and hip joint replacement, respectively. A total of 10 (31.2%) of 32 cultures from patients with periprosthetic infection after total hip joint replacement and 8 (17.8%) of 45 cultures from patients with periprosthetic infection after total knee joint replacement were positive. Overall, Staphylococcus aureus was detected in 9 (50%) of 18 positive cultures. Gram-negative aerobic bacteria (Acinetobacter baumannii, Klebsiella pneumoniae Pseudomonas aeruginosa) were detected in 4⁄10 and 5⁄8 of positive cultures from patients with periprosthetic infection of hip and knee joints, respectively.

Conclusions.

The most common pathogens causing periprosthetic infection of hip and knee joints were S. aureus (50%) and Gram-negative bacteria. The surgical treatment was performed in 71.4% of patients with periprosthetic joint infection.

Vladimir A. Ivantsov

Grodno State Medical University, Grodno, Belarus

Bogdanovich I.P.

Grodno State Medical University, Grodno, Belarus

Lashkovskiy V.V.

Grodno State Medical University, Grodno, Belarus

Anosov V.S.

Grodno State Medical University, Grodno, Belarus

  • 1. Preobrazhenskij P.M., Kazemirskij A.V., Goncharov M.Ju. Current views on the diagnosis and treatment of patients with periprosthetic infection after knee arthroplasty Genij ortopedii. 2016;3:94104. Russian. DOI: 10.18019/1028-4427-2016-3-94-104
  • 2. Voloshin V.P., Eremin A.V., Oshkurov S.A. Results of surgical treatment of a deep periprosthetic infection of the hip joint. Innovacionnye tehnologii v medicine. 2016;4(96):6770. Russian.
  • 3. Pavlov V.V., Sadovoj M.A., Prohorenko V.M. Modern aspects of diagnosis and surgical treatment of patients with periprosthetic infection of the hip joint (literature review). Travmatologija i ortopedija Rossii. 2015;1(75):116-128. Russian. DOI: 10.21823/2311-2905-2015-0-1-116-128
  • 4. Ivanov P.P., Kornilov N.N., Kulyba T.A. Surgical interventions for treatment of infected total knee arthroplasty (literature review). Kafedra travmatologii i ortopedii. 2017;1(21):37-43. Russian.
  • 5. Zubritsky V.F., Kozlov Ju.A. Infectious complications during large joint replacement. Vestnik Nacional'nogo mediko-hirurgicheskogo centra im. N.I. Pirogova. 2012;7(1):98-103. Russian.
  • 6. Garvin K.L., Kongsberg B.S. Infection follow in total knee arthroplasty: prevention and management. Instr Course Lect. 2012;61:411-419. PMID: 22301250
  • 7. Pichkhadze I.M., Kuzmenkov K.A., Zhadin A.V., Tsiskarashvili A.V., Pichkhadze E.I., Daneliya L.M., et al. Treatment of patients with pyo-inflammatory complications after hip replacement. Vestnik travmatologii i ortopedii im. N.N. Priorova. 2009;3:45-50. Russian.
  • 8. Baner T.W., Parvizi J., Kobayashi N., Krebs V. Diagnosis of periprostetic infection. J Bone Joint Surg Am. 2006;88(4):869882. DOI: 10.2106/JBJS.J.01413
  • 9. Barrett L., Atkins B. The clinical presentation of prosthetic joint infection. J Antimicrob Chemother. 2014;69(Suppl. 1):25-27. DOI: 10.1093/jac/dku250
  • 10. Vinkler T., Trampush A., Renc N., Perka K., Bozhkova S.A. Classification and algorithm for diagnosis and treatment of hip joint periprosthetic infection. Travmatologija i ortopedija Rossii. 2016;1(79):33-45. Russian.
  • 11. Proceedings of the International Consensus Meeting on Periprosthetic Joint Infection. Chairmen T. Gehrke, J. Parvizi. International Consensus Group LLC, 2013, p. 253-255.
  • 12. Crockarell J.R., Hanssen A.D., Osmon D.R., Morrey B.F. Treatment of infection with debridement and retention of the components following hip arthroplasty. J Bone Joint Surg. 1998;80(9):13061313. DOI: 10.2106/00004623-199809000-00009
  • 13. Waldman B.J., Hostin E., Mont M.A., Hunfergord D.S. Infected total knee arthroplasty treated by arthroscopic irrigation and debridement. J Arthropl. 2000;15(4):430-436. DOI: 10.1054/arth.2000.4637
  • 14. Microbiological methods for the study of biological material: Instructions for use: approved by the Ministry of Health of the Republic of Belarus 03/19/2010. Minsk. 129 р. Russian.
Views
0 Abstract
0 PDF
0 Crossref citations
Shared