Dalbavancin in the treatment of skin and soft tissue infections

Clinical Microbiology and Antimicrobial Chemotherapy. 2018; 20(4):320-340

​ Nikulin A.A., Khachatryan N.N.
10.36488/cmac.2018.4.320-340
dalbavancin MRSA skin and soft tissue infections
Section
Antimicrobials
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2018; 20(4):320-340

Abstract

Dalbavancin is a semi-synthetic lipoglycopeptide registered for the treatment of acute bacterial skin and skin structure infections caused by Gram-positive microorganisms, including MRSA. It has a prolonged half-life and excellent tissue levels which allows to its once-weekly administration. Article reviews data of in vitro, in vivo studies and clinical trials results, as well as potential indications of dalbavancin.

Anatoly A. Nikulin

Institute of Antimicrobial Chemotherapy, Smolensk State Medical University, Smolensk, Russia

Khachatryan N.N.

A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

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