A review of the Infectious Diseases Society of America (IDSA) guidelines on the diagnosis and treatment of spondylitis in adults | CMAC

A review of the Infectious Diseases Society of America (IDSA) guidelines on the diagnosis and treatment of spondylitis in adults

Clinical Microbiology and Antimicrobial Chemotherapy. 2017; 19(3):181-198

​ Karpov I.A., Gorbich Yu.L., Solovey N.V., Raznitsyna O.T.
vertebral osteomyelitis spondylitis spondylodiscitis antibacterial therapy
Section
Diseases and Pathogens
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2017; 19(3):181-198

Abstract

Spondylitis is a common disease in general clinical practice, which can be associated with a serious risk of adverse outcomes and severe disabling effects in case of late diagnosis and inadequate management of the patient. This article provides an overview of the current clinical guidelines of the Infectious Diseases Society of America (IDSA) on the diagnosis and treatment of spondylitis in adults.

Igor A. Karpov

Belorussian State Medical University, Minsk, Belarus

Gorbich Yu.L.

Belorussian State Medical University, Minsk, Belarus

Solovey N.V.

Belorussian State Medical University, Minsk, Belarus

Raznitsyna O.T.

Belorussian State Medical University, Minsk, Belarus

  • 1. Zimmerli W. Clinical practice. Vertebral osteomyelitis. N Engl J Med. 2010;362(11):1022-1029.
  • 2. Ablin G., Erickson T.C. Osteomyelitis of cervical vertebrae (and quadriparesis) secondary to urinary tract infection: case report and review of literature. J Neurosurg. 1958;15(4):455-459.
  • 3. Abram S.R., Tedeschi A.A., Partain C.L., Blumenkopf B. Differential diagnosis of severe back pain using MRI. South Med J. 1988;81(12):14871492.
  • 4. Gupta A., Kowalski T.J., Osmon D.R., et al. Long-term outcome of pyogenic vertebral osteomyelitis: a cohort study of 260 patients. Open Forum Infect Dis. 2014;1(3):ofu107.
  • 5. Chew F.S., Kline M.J. Diagnostic yield of CT-guided percutaneous aspiration procedures in suspected spontaneous infectious diskitis. Radiology. 2001;218(1):211-214.
  • 6. McHenry M.C., Easley K.A., Locker G.A. Vertebral osteomyelitis: long-term outcome for 253 patients from 7 Cleveland-area hospitals. Clin Infect Dis. 2002;34(10):1342-1350.
  • 7. Bettini N., Girardo M., Dema E., Cervellati S. Evaluation of conservative treatment of non specific spondylodiscitis. Eur Spine J. 2009;18(Suppl 1):143-150.
  • 8. Jensen A.G., Espersen F., Skinhøj P., Rosdahl V.T., Frimodt-Møller N. Increasing frequency of vertebral osteomyelitis following Staphylococcus aureus bacteraemia in Denmark 1980-1990. J Infect. 1997;34(2):113118.
  • 9. Mylona E., Samarkos M., Kakalou E., Fanourgiakis P., Skoutelis A. Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Semin Arthritis Rheum. 2009;39(1):10-17.
  • 10. Corrah T.W., Enoch D.A., Aliyu S.H., Lever A.M. Bacteraemia and subsequent vertebral osteomyelitis: a retrospective review of 125 patients. QJM. 2011;104(3):201-207.
  • 11. Livorsi D.J., Daver N.G., Atmar R.L., et al. Outcomes of treatment for hematogenous Staphylococcus aureus vertebral osteomyelitis in the MRSA ERA. J Infect. 2008;57(2):128-131.
  • 12. Bhavan K.P., Kirmani N. Hematogenous vertebral osteomyelitis. Mo Med. 2009;106(4):277-282.
  • 13. Chelsom J., Solberg C.O. Vertebral osteomyelitis at a Norwegian university hospital 1987-97: clinical features, laboratory findings and outcome. Scand J Infect Dis. 1998;30(2):147-151.
  • 14. Carragee E.J., Kim D., van der Vlugt T., Vittum D. The clinical use of erythrocyte sedimentation rate in pyogenic vertebral osteomyelitis. Spine. 1997;22(18):2089-2093.
  • 15. Kowalski T.J., Berbari E.F., Huddleston P.M., Steckelberg J.M., Osmon D.R. Do follow-up imaging examinations provide useful prognostic information in patients with spine infection? Clin Infect Dis. 2006;43(2):172-179.
  • 16. Kowalski T.J., Berbari E.F., Huddleston P.M., Steckelberg J.M., Osmon D.R. Propionibacterium acnes vertebral osteomyelitis: seek and ye shall find? Clin Orthop Relat Res. 2007;461:25-30.
  • 17. Brozek J.L., Akl E.A., Jaeschke R., et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines: Part 2 of 3. The GRADE approach to grading quality of evidence about diagnostic tests and strategies. Allergy. 2009;64(8):1109-1116.
  • 18. Guyatt G.H., Oxman A.D., Kunz R., et al. Going from evidence to recommendations. BMJ. 2008;336(7652):1049-1051.
  • 19. Guyatt G.H., Oxman A.D., Vist G.E., et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924-926.
  • 20. Schünemann H.J., Schünemann A.H.J., Oxman A.D., et al. Grading quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ. 2008;336(7653):1106-1110.
  • 21. Grammatico L., Baron S., Rusch E., et al. Epidemiology of vertebral osteomyelitis (VO) in France: analysis of hospital-discharge data 20022003. Epidemiol Infect. 2008;136(5):653-660.
  • 22. CASE RECORDS of the Massachusetts General Hospital; weekly clinicopathological exercises; case 44012. N Engl J Med. 1958;258(1): 42-45.
  • 23. Sharma S.K., Jones J.O., Zeballos P.P., Irwin S.A., Martin T.W. The prevention of discitis during discography. Spine J. 2009;9(11):936-943.
  • 24. Berbari E.F., Kanj S.S., Kowalski T.J., et al. 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults. Clin Infect Dis. 2015;61(6):e26-46.
  • 25. Gasbarrini A.L., Bertoldi E., Mazzetti M., et al. Clinical features, diagnostic and therapeutic approaches to haematogenous vertebral osteomyelitis. Eur Rev Med Pharmacol Sci. 2005;9(1):53-66.
  • 26. Buranapanitkit B., Lim A., Geater A. Misdiagnosis in vertebral osteomyelitis: problems and factors. J Med Assoc Thai. 2001;84(12):1743-1750.
  • 27. Hsiao M.-Y., Liang H.-W. Delayed diagnosis of vertebral osteomyelitis in a paraplegic patient. Spinal Cord. 2011;49(9):1020-1022.
  • 28. Siemionow K., Lieberman I.H. Surgical approaches to metastatic spine disease. Curr Opin Support Palliat Care. 2008;2(3):192-196.
  • 29. Torda A.J., Gottlieb T., Bradbury R. Pyogenic vertebral osteomyelitis: analysis of 20 cases and review. Clin Infect Dis. 1995;20(2):320-328.
  • 30. Skaf G.S., Domloj N.T., Fehlings M.G., et al. Pyogenic spondylodiscitis: an overview. J Infect Public Health. 2010;3(1):5-16.
  • 31. Oztekin O., Calli C., Adibelli Z., et al. Brucellar spondylodiscitis: magnetic resonance imaging features with conventional sequences and diffusionweighted imaging. Radiol Med. 2010;115(5):794-803.
  • 32. Goertz C.E.C., Frasca S., Bohach G.A., et al. Brucella sp. vertebral osteomyelitis with intercurrent fatal Staphylococcus aureus toxigenic enteritis in a bottlenose dolphin (Tursiops truncatus). J Vet Diagn Invest. 2011;23(4):845-851.
  • 33. Kraniotis P., Marangos M., Lekkou A., Romanos O., Solomou E. Brucellosis presenting as piriformis myositis: a case report. J Med Case Rep. 2011;5:125.
  • 34. Mrabet D., Mizouni H., Khiari H., et al. Brucellar spondylodiscitis affecting non-contiguous spine levels. BMJ Case Rep. 2011;10.1136/ bcr.01.2011.3788.
  • 35. Song K.-J., Yoon S.J., Lee K.-B. Cervical spinal brucellosis with epidural abscess causing neurologic deficit with negative serologic tests. World Neurosurg. 2012;78(3-4):375.e15-19.
  • 36. Wong-Chung J.K., Naseeb S.A., Kaneker S.G., Aradi A.J. Anterior disc protrusion as a cause for abdominal symptoms in childhood discitis. A case report. Spine. 1999;24(9):918-920.
  • 37. Siemionow K., Steinmetz M., Bell G., Ilaslan H., McLain R.F. Identifying serious causes of back pain: cancer, infection, fracture. Cleve Clin J Med. 2008;75(8):557-566.
  • 38. Jensen A.G., Espersen F., Skinhøj P., Frimodt-Møller N. Bacteremic Staphylococcus aureus spondylitis. Arch Intern Med. 1998;158(5):509517.
  • 39. Schininà V., Rizzi E.B., Rovighi L., et al. Infectious spondylodiscitis: magnetic resonance imaging in HIV-infected and HIV-uninfected patients. Clin Imaging. 2001;25(5):362-367.
  • 40. Bozgeyik Z., Ozdemir H., Demirdag K., et al. Clinical and MRI findings of brucellar spondylodiscitis. Eur J Radiol. 2008;67(1):153-158.
  • 41. Ledermann H.P., Schweitzer M.E., Morrison W.B., Carrino J.A. MR imaging findings in spinal infections: rules or myths? Radiology. 2003;228(2):506514.
  • 42. Dagirmanjian A., Schils J., McHenry M., Modic M.T. MR imaging of vertebral osteomyelitis revisited. AJR Am J Roentgenol. 1996;167(6):15391543.
  • 43. Ozaksoy D., Yücesoy K., Yücesoy M., et al. Brucellar spondylitis: MRI findings. Eur Spine J. 2001;10(6):529-533.
  • 44. Dunbar J.A., Sandoe J.A., Rao A.S., et al. The MRI appearances of early vertebral osteomyelitis and discitis. Clin Radiol. 2010;65(12):974-981.
  • 45. Love C., Patel M., Lonner B.S., Tomas M.B., Palestro C.J. Diagnosing spinal osteomyelitis: a comparison of bone and Ga-67 scintigraphy and magnetic resonance imaging. Clin Nucl Med. 2000;25(12):963-977.
  • 46. Palestro C.J., Torres M.A. Radionuclide imaging in orthopedic infections. Semin Nucl Med. 1997;27(4):334-345.
  • 47. Datz F.L. Indium-111-labeled leukocytes for the detection of infection: current status. Semin Nucl Med. 1994;24(2):92-109.
  • 48. Ohtori S., Suzuki M., Koshi T., et al. 18F-fluorodeoxyglucose-PET for patients with suspected spondylitis showing Modic change. Spine. 2010;35(26):E1599-1603.
  • 49. Lee A., Mirrett S., Reller L.B., Weinstein M.P. Detection of bloodstream infections in adults: how many blood cultures are needed? J Clin Microbiol. 2007;45(11):3546-3548.
  • 50. Patel R., Vetter E.A., Harmsen W.S., et al. Optimized pathogen detection with 30- compared to 20-milliliter blood culture draws. J Clin Microbiol. 2011;49(12):4047-4051.
  • 51. Araj G.F., Kattar M.M., Fattouh L.G., Bajakian K.O., Kobeissi S.A. Evaluation of the PANBIO Brucella immunoglobulin G (IgG) and IgM enzyme-linked immunosorbent assays for diagnosis of human brucellosis. Clin Diagn Lab Immunol. 2005;12(11):1334-1335.
  • 52. Skaf G.S., Kanafani Z.A., Araj G.F., Kanj S.S. Non-pyogenic infections of the spine. Int J Antimicrob Agents. 2010;36(2):99-105.
  • 53. Herron L.D., Kissel P., Smilovitz D. Treatment of coccidioidal spinal infection: experience in 16 cases. J Spinal Disord. 1997;10(3):215-222.
  • 54. Sapico F.L., Montgomerie J.Z. Vertebral osteomyelitis. Infect Dis Clin North Am. 1990;4(3):539-550.
  • 55. Kelesidis T., Theodoros K., Tsiodras S., Sotirios T. Successful treatment of azole-resistant Candida spondylodiscitis with high-dose caspofungin monotherapy. Rheumatol Int. 2012;32(9):2957-2958.
  • 56. Joshi T.N. Candida albicans spondylodiscitis in an immunocompetent patient. J Neurosci Rural Pract. 2012;3(2):221-222.
  • 57. Jorge V.C., Cardoso C., Noronha C., et al. “Fungal spondylodiscitis in a non-immunocompromised patient.” BMJ Case Rep. 2012;10.1136/ bcr.12.2011.5337.
  • 58. Werner B.C., Hogan M.V., Shen F.H. Candida lusitaniae discitis after discogram in an immunocompetent patient. Spine J. 2011;11(10):e1-6.
  • 59. Rachapalli S.M., Malaiya R., Mohd T.A., Hughes R.A. Successful treatment of Candida discitis with 5-flucytosine and fluconazole. Rheumatol Int. 2010;30(11):1543-1544.
  • 60. Cho K., Lee S.-H., Kim E.-S., Eoh W. Candida parapsilosis spondylodiscitis after lumbar discectomy. J Korean Neurosurg Soc. 2010;47(4):295-297.
  • 61. Moon H.H., Kim J.H., Moon B.G., Kim J.S. Cervical spondylodiscitis caused by Candida albicans in non-immunocompromised patient. J Korean Neurosurg Soc. 2008;43(1):45-47.
  • 62. Walsh T.J., Anaissie E.J., Denning D.W., et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis. 2008;46(3):327-360.
  • 63. Chapman S.W., Dismukes W.E., Proia L.A., et al. Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America. Clin Infect Dis. 2008;46(12):18011812.
  • 64. Galgiani J.N., Ampel N.M., Blair J.E., et al. Coccidioidomycosis. Clin Infect Dis. 2005;41(9):1217-1223.
  • 65. Pappas P.G., Kauffman C.A., Andes D., et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;48(5):503-535.
  • 66. Wheat L.J., Freifeld A.G., Kleiman M.B., et al. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis. 2007;45(7):807825.
  • 67. Ramos A., Huddleston P.M., Patel R., Vetter E., Berbari E.F. Vertebral osteomyelitis due to Candida species: a cohort study and review of the literature. Open J Orthop. 2013;3:81-89.
  • 68. De Backer A.I., Mortelé K.J., Vanschoubroeck I.J., et al. Tuberculosis of the spine: CT and MR imaging features. JBR-BTR. 2005;88(2):92-97.
  • 69. Menzies D., Pai M., Comstock G. Meta-analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research. Ann Intern Med. 2007;146(5):340-354.
  • 70. Yuan K., Zhong Z., Zhang Q., Xu S., Chen J. Evaluation of an enzyme-linked immunospot assay for the immunodiagnosis of atypical spinal tuberculosis (atypical clinical presentation/atypical radiographic presentation) in China. Braz J Infect Dis. 2013;17(5):529-537.
  • 71. Michel S.C.A., Pfirrmann C.W.A., Boos N., Hodler J. CT-guided core biopsy of subchondral bone and intervertebral space in suspected spondylodiskitis. AJR Am J Roentgenol. 2006;186(4):977-980.
  • 72. de Lucas E.M., González Mandly A., Gutiérrez A., et al. CT-guided fineneedle aspiration in vertebral osteomyelitis: true usefulness of a common practice. Clin Rheumatol. 2009;28(3):315-320.
  • 73. Kornblum M.B., Wesolowski D.P., Fischgrund J.S., Herkowitz H.N. Computed tomography-guided biopsy of the spine. A review of 103 patients. Spine. 1998;23(1):81-85.
  • 74. Sehn J.K., Gilula L.A. Percutaneous needle biopsy in diagnosis and identification of causative organisms in cases of suspected vertebral osteomyelitis. Eur J Radiol. 2012;81(5):940-946.
  • 75. Fouquet B., Goupille P., Gobert F., et al. Infectious discitis diagnostic contribution of laboratory tests and percutaneous discovertebral biopsy. Rev Rhum Engl Ed. 1996; 63(1):24-29.
  • 76. Olscamp A., Rollins J., Tao S.S., Ebraheim N.A. Complications of CTguided biopsy of the spine and sacrum. Orthopedics. 1997;20(12):11491152.
  • 77. Jensen A.G. Staphylococcus aureus bacteremia. Dan Med Bull. 2003;50(4):423-438.
  • 78. Greig J.M., Wood M.J. Staphylococcus lugdunensis vertebral osteomyelitis. Clin Microbiol Infect. 2003;9(11):1139-1141.
  • 79. Murdoch D.R., Everts R.J., Chambers S.T, Cowan I.A. Vertebral osteomyelitis due to Staphylococcus lugdunensis. J Clin Microbiol. 1996;34(4):993994.
  • 80. Cervan A.M., Colmenero J. de D., Del Arco A., Villanueva F., Guerado E. Spondylodiscitis in patients under haemodyalisis. Int Orthop. 2012;36(2):421-426.
  • 81. Faria B., Canto Moreira N., Sousa T.C., et al. Spondylodiscitis in hemodialysis patients: a case series. Clin Nephrol. 2011;76(5):380-387.
  • 82. Solera J., Lozano E., Martínez-Alfaro E., et al. Brucellar spondylitis: review of 35 cases and literature survey. Clin Infect Dis. 1999;29(6):1440-1449.
  • 83. Binnicker M.J., Theel E.S., Larsen S.M., Patel R. A high percentage of serum samples that test reactive by enzyme immunoassay for anti-Brucella antibodies are not confirmed by the standard tube agglutination test. Clin Vaccine Immunol. 2012;19(8):1332-1334.
  • 84. Rankine J.J., Barron D.A., Robinson P., Millner P.A., Dickson R.A. Therapeutic impact of percutaneous spinal biopsy in spinal infection. Postgrad Med J. 2004;80(948):607-609.
  • 85. Hassoun A., Taur Y., Singer C. Evaluation of thin needle aspiration biopsy in the diagnosis and management of vertebral osteomyelitis (VO). Int J Infect Dis. 2006;10(6):486-487.
  • 86. Kim C.-J., Song K.-H., Park W.B., et al. Microbiologically and clinically diagnosed vertebral osteomyelitis: impact of prior antibiotic exposure. Antimicrob Agents Chemother. 2012;56(4):2122-2124.
  • 87. Marschall J., Bhavan K.P., Olsen M.A., et al. The impact of prebiopsy antibiotics on pathogen recovery in hematogenous vertebral osteomyelitis. Clin Infect Dis. 2011;52(7):867-872.
  • 88. Trampuz A., Piper K.E., Jacobson M.J., et al. Sonication of removed hip and knee prostheses for diagnosis of infection. N Engl J Med. 2007;357(7):654-663.
  • 89. Grados F., Lescure F.X., Senneville E., et al. Suggestions for managing pyogenic (non-tuberculous) discitis in adults. Joint Bone Spine. 2007;74(2):133-139.
  • 90. Mete B., Kurt C., Yilmaz M.H., et al. Vertebral osteomyelitis: eight years’ experience of 100 cases. Rheumatol Int. 2012;32(11):3591-3597.
  • 91. Sakkas L.I., Davas E.M., Kapsalaki E., et al. Hematogenous spinal infection in central Greece. Spine. 2009;34(15):E513-518.
  • 92. Memish Z.A., Balkhy H.H. Brucellosis and international travel. J Travel Med. 2004;11(1):49-55.
  • 93. Colmenero J.D., Ruiz-Mesa J.D., Plata A., et al. Clinical findings, therapeutic approach, and outcome of brucellar vertebral osteomyelitis. Clin Infect Dis. 2008;46(3):426-433.
  • 94. Froissart A., Pagnoux C., Chérin P. Lymph node paradoxical enlargement during treatment for tuberculous spondylodiscitis (Pott’s disease). Joint Bone Spine. 2007;74(3):292-295.
  • 95. Gouliouris T., Aliyu S.H., Brown N.M. Spondylodiscitis: update on diagnosis and management. J Antimicrob Chemother. 2010;65(Suppl 3):iii11-24.
  • 96. Lifeso R. Atlanto-axial tuberculosis in adults. J Bone Joint Surg Br. 1987;69(2):183-187.
  • 97. Berk R.H., Yazici M., Atabey N., et al. Detection of Mycobacterium tuberculosis in formaldehyde solution-fixed, paraffin-embedded tissue by polymerase chain reaction in Pott’s disease. Spine. 1996;21(17):19911995.
  • 98. Kim C.-J., Song K.-H., Jeon J.-H., et al. A comparative study of pyogenic and tuberculous spondylodiscitis. Spine. 2010;35(21):E1096-1100.
  • 99. Colmenero J.D., Jiménez-Mejías M.E., Sánchez-Lora F.J., et al. Pyogenic, tuberculous, and brucellar vertebral osteomyelitis: a descriptive and comparative study of 219 cases. Ann Rheum Dis. 1997;56(12):709-715.
  • 100. Arizono T., Oga M., Shiota E., Honda K., Sugioka Y. Differentiation of vertebral osteomyelitis and tuberculous spondylitis by magnetic resonance imaging. Int Orthop. 1995;19(5):319-322.
  • 101. Petitjean G., Fluckiger U., Schären S., Laifer G. Vertebral osteomyelitis caused by non-tuberculous mycobacteria. Clin Microbiol Infect. 2004;10(11):951-953.
  • 102. Josephson C.B., Al-Azri S., Smyth D.J, Haase D., Johnston B.L. A case of Pott’s disease with epidural abscess and probable cerebral tuberculoma following Bacillus Calmette-Guérin therapy for superficial bladder cancer. Can J Infect Dis Med Microbiol. 2010;21(1):e75-78.
  • 103. Bhavan K.P., Marschall J., Olsen M.A., et al. The epidemiology of hematogenous vertebral osteomyelitis: a cohort study in a tertiary care hospital. BMC Infect Dis. 2010;10:158.
  • 104. Turunc T., Demiroglu Y.Z., Uncu H., Colakoglu S., Arslan H. A comparative analysis of tuberculous, brucellar and pyogenic spontaneous spondylodiscitis patients. J Infect. 2007;55(2):158-163.
  • 105. Fuursted K., Arpi M., Lindblad B.E., Pedersen L.N. Broad-range PCR as a supplement to culture for detection of bacterial pathogens in patients with a clinically diagnosed spinal infection. Scand J Infect Dis. 2008;40(10):772777.
  • 106. Navarro E., Segura J.C., Castaño M.J., Solera J. Use of real-time quantitative polymerase chain reaction to monitor the evolution of Brucella melitensis DNA load during therapy and post-therapy follow-up in patients with brucellosis. Clin Infect Dis. 2006;42(9):1266-1273.
  • 107. Navarro-Martínez A., Navarro E., Castaño M.J., Solera J. Rapid diagnosis of human brucellosis by quantitative real-time PCR: a case report of brucellar spondylitis. J Clin Microbiol. 2008; 46(1):385-387.
  • 108. Chen S.C.A., Halliday C.L., Meyer W. A review of nucleic acid-based diagnostic tests for systemic mycoses with an emphasis on polymerase chain reaction-based assays. Med Mycol. 2002;40(4):333-357.
  • 109. Lis E., Bilsky M.H., Pisinski L., et al. Percutaneous CT-guided biopsy of osseous lesion of the spine in patients with known or suspected malignancy. AJNR Am J Neuroradiol. 2004;25(9):1583-1588.
  • 110. Wu J.S., Gorbachova T., Morrison W.B., Haims A.H. Imaging-guided bone biopsy for osteomyelitis: are there factors associated with positive or negative cultures? AJR Am J Roentgenol. 2007;188(6):1529-1534.
  • 111. Babu N.V., Titus V.T., Chittaranjan S., et al. Computed tomographically guided biopsy of the spine. Spine. 1994;19(21):2436-2442.
  • 112. Peh W. CT-guided percutaneous biopsy of spinal lesions. Biomed Imaging Interv J. 2006;2(3):e25.
  • 113. Priest D.H., Peacock J.E. Hematogenous vertebral osteomyelitis due to Staphylococcus aureus in the adult: clinical features and therapeutic outcomes. South Med J. 2005;98(9):854-862.
  • 114. Yang S.-C., Fu T.-S., Chen L.-H., et al. Percutaneous endoscopic discectomy and drainage for infectious spondylitis. Int Orthop. 2007;31(3):367-373.
  • 115. Cotty P., Fouquet B., Pleskof L., et al. Vertebral osteomyelitis: value of percutaneous biopsy. 30 cases. J Neuroradiol. 1988;15(1):13-21.
  • 116. Parker L.M., McAfee P.C., Fedder I.L., Weis J.C., Geis W.P. Minimally invasive surgical techniques to treat spine infections. Orthop Clin North Am. 1996;27(1):183-199.
  • 117. Staatz G., Adam G.B., Keulers P., Vorwerk D., Günther R.W. Spondylodiskitic abscesses: CT-guided percutaneous catheter drainage. Radiology. 1998;208(2):363-367.
  • 118. Vinicoff P.G., Gutschik E., Hansen S.E., Karle A., Rieneck K. [CT-guided spinal biopsy in spondylodiscitis]. Ugeskr Laeg. 1998;160(41):59315934.
  • 119. Haaker R.G., Senkal M., Kielich T., Krämer J. Percutaneous lumbar discectomy in the treatment of lumbar discitis. Eur Spine J. 1997;6(2):98101.
  • 120. Ito M., Abumi K., Kotani Y., Kadoya K., Minami A. Clinical outcome of posterolateral endoscopic surgery for pyogenic spondylodiscitis: results of 15 patients with serious comorbid conditions. Spine. 2007;32(2):200206.
  • 121. Yang S.-C., Fu T.-S., Chen L.-H., Chen W.-J., Tu Y.-K. Identifying pathogens of spondylodiscitis: percutaneous endoscopy or CT-guided biopsy. Clin Orthop Relat Res. 2008;466(12):3086-3092.
  • 122. Viale P., Furlanut M., Scudeller L., et al. Treatment of pyogenic (nontuberculous) spondylodiscitis with tailored high-dose levofloxacin plus rifampicin. Int J Antimicrob Agents. 2009;33(4):379-382.
  • 123. Liu C., Bayer A., Cosgrove S.E., et al. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillinresistant Staphylococcus aureus infections in adults and children: executive summary. Clin Infect Dis. 2011;52(3):285-292.
  • 124. Baddour L.M., Wilson W.R., Bayer A.S., et al. Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. Circulation. 2005;111(23):e394-434.
  • 125. Graninger W., Ragette R. Nosocomial bacteremia due to Enterococcus faecalis without endocarditis. Clin Infect Dis. 1992;15(1):49-57.
  • 126. Tice A.D., Rehm S.J., Dalovisio J.R., et al. Practice guidelines for outpatient parenteral antimicrobial therapy. IDSA guidelines. Clin Infect Dis. 2004;38(12):1651-1672.
  • 127. Bernard L., Dinh A., Ghout I., et al. Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial. Lancet. 2015;385(9971):875882.
  • 128. Legrand E., Flipo R.M., Guggenbuhl P., et al. Management of nontuberculous infectious discitis. treatments used in 110 patients admitted to 12 teaching hospitals in France. Joint Bone Spine. 2001;68(6):504509.
  • 129. Roblot F., Besnier J.M., Juhel L., et al. Optimal duration of antibiotic therapy in vertebral osteomyelitis. Semin Arthritis Rheum. 2007;36(5):269-277.
  • 130. Babouee Flury B., Elzi L., Kolbe M., et al. Is switching to an oral antibiotic regimen safe after 2 weeks of intravenous treatment for primary bacterial vertebral osteomyelitis? BMC Infect Dis. 2014;14:226.
  • 131. Lazzarini L., Lipsky B.A., Mader J.T. Antibiotic treatment of osteomyelitis: what have we learned from 30 years of clinical trials? Int J Infect Dis. 2005;9(3):127-138.
  • 132. Lazzarini L., De Lalla F., Mader J.T. Long Bone Osteomyelitis. Curr Infect Dis Rep. 2002;4(5):439-445.
  • 133. Gentry L.O. Antibiotic therapy for osteomyelitis. Infect Dis Clin North Am. 1990;4(3):485-499.
  • 134. Carek P.J., Dickerson L.M., Sack J.L. Diagnosis and management of osteomyelitis. Am Fam Physician. 2001;63(12):2413-2420.
  • 135. Daver N.G., Shelburne S.A., Atmar R.L., et al. Oral step-down therapy is comparable to intravenous therapy for Staphylococcus aureus osteomyelitis. J Infect. 2007;54(6):539-544.
  • 136. Rissing J.P. Antimicrobial therapy for chronic osteomyelitis in adults: role of the quinolones. Clin Infect Dis. 1997;25(6):1327-1333.
  • 137. Swiontkowski M.F., Hanel D.P., Vedder N.B., Schwappach J.R. A comparison of short- and long-term intravenous antibiotic therapy in the postoperative management of adult osteomyelitis. J Bone Joint Surg Br. 1999;81(6):1046-1050.
  • 138. American Thoracic Society, CDC, Infectious Diseases Society of America. Treatment of tuberculosis. MMWR Recomm Rep. 2003;52(RR-11):1-77.
  • 139. Chen W.-H., Jiang L.-S., Dai L.-Y. Surgical treatment of pyogenic vertebral osteomyelitis with spinal instrumentation. Eur Spine J. 2007;16(9):13071316.
  • 140. Valancius K., Hansen E.S., Høy K., et al. Failure modes in conservative and surgical management of infectious spondylodiscitis. Eur Spine J. 2013;22(8):1837-1844.
  • 141. Kulowski J. THE ORR TREATMENT OF PYOGENIC OSTEOMYELITIS. Ann Surg. 1936;103(4):613-624.
  • 142. Carragee E.J. Pyogenic vertebral osteomyelitis. J Bone Joint Surg Am. 1997;79(6):874-880.
  • 143. Nolla J.M., Ariza J., Gómez-Vaquero C., et al. Spontaneous pyogenic vertebral osteomyelitis in nondrug users. Semin Arthritis Rheum. 2002; 31(4):271-278.
  • 144. Wang Q., Babyn P., Branson H., et al. Utility of MRI in the follow-up of pyogenic spinal infection in children. Pediatr Radiol. 2010;40(1):118130.
  • 145. Carragee E.J. Instrumentation of the infected and unstable spine: a review of 17 cases from the thoracic and lumbar spine with pyogenic infections. J Spinal Disord. 1997;10(4):317-324.
  • 146. Solis Garcia del Pozo J., Vives Soto M., Solera J. Vertebral osteomyelitis: long-term disability assessment and prognostic factors. J Infect. 2007;54(2):129-134.
  • 147. O’Daly B.J., Morris S.F., O’Rourke S.K. Long-term functional outcome in pyogenic spinal infection. Spine. 2008;33(8):E246-253.
  • 148. Kowalski T.J., Layton K.F., Berbari E.F., et al. Follow-up MR imaging in patients with pyogenic spine infections: lack of correlation with clinical features. AJNR Am J Neuroradiol. 2007;28(4):693-699.
  • 149. Carragee E.J. The clinical use of magnetic resonance imaging in pyogenic vertebral osteomyelitis. Spine. 1997;22(7):780-785.
  • 150. Khan M.H., Smith P.N., Rao N., Donaldson W.F. Serum C-reactive protein levels correlate with clinical response in patients treated with antibiotics for wound infections after spinal surgery. Spine J. 2006;6(3):311-315.
  • 151. Yoon S.H., Chung S.K., Kim K.-J., et al. Pyogenic vertebral osteomyelitis: identification of microorganism and laboratory markers used to predict clinical outcome. Eur Spine J. 2010;19(4):575-582.
  • 152. Veillard E., Guggenbuhl P., Morcet N., et al. Prompt regression of paravertebral and epidural abscesses in patients with pyogenic discitis. Sixteen cases evaluated using magnetic resonance imaging. Joint Bone Spine. 2000;67(3):219-227.
  • 153. Euba G., Narváez J.A., Nolla J.M., et al. Long-term clinical and radiological magnetic resonance imaging outcome of abscess-associated spontaneous pyogenic vertebral osteomyelitis under conservative management. Semin Arthritis Rheum. 2008;38(1):28-40.
  • 154. Zarrouk V., Feydy A., Sallès F., et al. Imaging does not predict the clinical outcome of bacterial vertebral osteomyelitis. Rheumatology (Oxford). 2007;46(2):292-295.
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