antibacterial therapy | CMAC

antibacterial therapy

Practical guidelines for antibiotic prescribing in breast surgery: antibiotic prophylaxis and treatment of surgical site infections and implant-associated infections

Breast surgery is a broad field that includes both surgical treatment of breast diseases and various variants of reconstructive and plastic surgeries for breast correction. Despite the fact that according to the accepted classification breast …

Infectious endocarditis caused by Cutibacterium avidum in a patient with endocardial pacemaker and multiple drug hypersensitivity reactions: a clinical case

Cutibacterium avidum is a well-known skin commensal, that sometimes can cause superficial or invasive infections, including infectious endocarditis. Cases of C. avidum-induced infectious endocarditis of native heart valves, prosthetic valves or other …

Piperacillin-tazobactam in the treatment of severe intra-abdominal and urinary tract infections in the Russian Federation

Piperacillin/tazobactam is a well-known β-lactam antibiotic that has been used in clinical practice since 1993. The review presents the clinical and pharmacological characteristics of piperacillin-tazobactam, the results of clinical studies and …

Difficulties in choosing antibacterial therapy regimen for nosocomial pneumonia in intensive care units: clinical observations

Nosocomial pneumonia is one of the most common healthcare-associated infections and the most frequent in intensive care unit (ICU) patients. The clinical and economic consequences of nosocomial pneumonia are very significant, especially for …

Infective endocarditis caused by Klebsiella pneumoniae in a patient with non ST elevation myocardial infarction

A rare clinical case of native aortic valve infective endocarditis (IE) caused by Klebsiella pneumoniae in a 56-year old man without known risk factors predisposing to the development of IE is presented. Diagnosis of IE in this patient was a …

COVID19 pandemic is a «pandemic» of antimicrobial therapy

The article presents a critical analysis of antibiotic usage tactics in the treatment of patients with COVID-19 existing in Russian and foreign healthcare, and discusses the possible causes of unjustified antibiotic aggression in this category of …

Biomarkers of infection in the optimization of antibacterial therapy: justified expectations

Despite the continuous improvement of approaches to antimicrobial therapy and the emergence of new highly effective antibiotics, severe bacterial infections being a significant cause of morbidity and mortality remain a top of mind issue for …

Potential for the use of macrolides in the antimicrobial therapy of severe community-acquired pneumonia in adults

This paper presents mechanism of action and antimicrobial spectrum of macrolides as well as the known acquired resistance mechanisms in the common pathogens causing community-acquired pneumonia, such as Streptococcus pneumoniae and Mycoplasma …

Antibiotics and community-acquired lower respiratory tract infections. To whom? Which one?

This paper discusses an etiology, patient characteristics, and antimicrobial resistance surveillance data, as well as other factors which help to determine indications for administration and choice of antibiotics for the treatment of patients with …

Infectious endocarditis caused by Gemella haemolysans: clinical issues and treatment approaches

Gemella haemolysans is a commensal of the human oral cavity, upper respiratory tract, and gastrointestinal tract, which in some cases can cause serious infections, including infective endocarditis (IE). IE caused by G. haemolysans is more common in …