Clinical Microbiology and Antimicrobial Chemotherapy. 2015; 17(4):310-317
This article presents current view about the mechanisms of human gut microbiota influence on chronic systemic inflammation. Over the last years, evidence of close relationship between different medical conditions and gut microbiota status has been obtained. Epidemiological and clinical studies confirmed an association between immune system function and gut microbiota composition. Also, it has been found that qualitative and quantitative changes in gut microbiota could induce or inhibit chronic inflammation and, therefore, influence on the development of non-infectious diseases, such as type 2 diabetes, cardiovascular diseases, allergic reactions etc.