The Involvement of Human Gut Microbiota in Chronic Systemic Inflammation

Clinical Microbiology and Antimicrobial Chemotherapy. 2015; 17(4):310-317

​ Kashtanova D.A., Egshatyan L.V., Tkacheva O.N.
chronic inflammation gut microbiota pro-inflammatory mediators lipopolysaccharide lipoteichoic acid peptidoglycan regulatory T-cells
Section
Personal Experience
Type
Journal article
Publication
Clinical Microbiology and Antimicrobial Chemotherapy. 2015; 17(4):310-317

Abstract

This article presents current view about the mechanisms of human gut microbiota influence on chronic systemic inflammation. Over the last years, evidence of close relationship between different medical conditions and gut microbiota status has been obtained. Epidemiological and clinical studies confirmed an association between immune system function and gut microbiota composition. Also, it has been found that qualitative and quantitative changes in gut microbiota could induce or inhibit chronic inflammation and, therefore, influence on the development of non-infectious diseases, such as type 2 diabetes, cardiovascular diseases, allergic reactions etc.

Darya A. Kashtanova

National Research Center for Preventive Medicine, Moscow, Russia

Lilit V. Egshatyan

National Research Center for Preventive Medicine, Moscow, Russia

Tkacheva O.N.

National Research Center for Preventive Medicine, Moscow, Russia

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