lipopolysaccharide

Objective. To determine functional anti-LPS specific serum bactericidal antibody (SBA) and opsonophagocytic killing antibody (OPKA) activities in mice immunized with a pentavalent candidate vaccine against Shigella flexneri 1b, 2a, 3a, 6, Y (PF). Materials and Methods. (CBA x C57 B1/6) F1 mice were immunized with a PF. 14 days after the reimmunization, serum samples were collected and the level of specific IgG in them was determined by ELISA. The sera of mice immunized with individual modified lipopolysaccharides (mLPS), which are part of PF, were used for positive control.

This article is an overview of the data on bacterial intestinal translocation. The article reviews changes in the intestinal microbiome, the local physiological barrier, as well as the innate and adaptive immunity characteristics contributing to the …

This article presents current view about the mechanisms of human gut microbiota influence on chronic systemic inflammation. Over the last years, evidence of close relationship between different medical conditions and gut microbiota status has been …