Clinical Microbiology and Antimicrobial Chemotherapy. 2013; 15(3):219-229
Antimicrobial susceptibility testing is an important and one of the most time-consuming and expensive procedures in microbiological laboratory. Use of appropriate panel of antibiotics along with correct identification of isolated pathogen make it possible to assume resistance mechanisms in the tested isolate and predict its susceptibility (resistance) to similar (by structure and/or mechanism of action) antimicrobial agents. This review describes principles of antibiotic choice for in vitro susceptibility testing as well as rules of testing results interpretation. Adherence to these principles and rules provides as many information as possible for administration of effective antibacterial therapy.