Phenotypic and Genotypic Characteristics of Pneumococci Isolated from Patients with Pneumococcal Meningitis | CMAC

Phenotypic and Genotypic Characteristics of Pneumococci Isolated from Patients with Pneumococcal Meningitis

Clinical Microbiology and Antimicrobial Chemotherapy. 2011; 13(3):261-266

Type
Journal article

Abstract

Antimicrobial susceptibility, serotype distribution, and multilocus sequence types of Streptococcus pneumoniae isolated from the patients with meningitis were determined. We tested a total of 84 isolates which have been obtained in Moscow during 1980-2010, of them 20 isolates were non-susceptible to penicillin. Serotypes 19F, 19A, 23F, 6A, 6B and 14 were the leading serotypes among the resistance strains. Eight of the 11 strains non-susceptible to penicillin, which were isolated from 2008 to 2010, belonged to new sequence types not hitherto described in the MLST database. The two isolates appeared to be clonally related to the Spain 23F-1 and Taiwan 19F-14 clones by MLST.

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