Etiology of Diabetic Foot Infections and In Vitro Activity of Antimicrobial Agents

Clinical Microbiology and Antimicrobial Chemotherapy. 2009; 11(1):86-89

Journal article


This article presents the results of the study to determine etiology and antimicrobial susceptibility in diabetic foot infections (DFI). A total of 288 isolates were obtained from patients with confirmed DFI by fine-needle aspiration/biopsy during the period of 2006–2008. Aerobes were isolated more frequently than anaerobes (74.6% versus 25.4%). Infections were polymicrobial in 83.5% of cases (aerobic combinations – 54.9%, aerobes + anaerobes – 24.2%). The most common gram-positive and gram-negative pathogens were S. aureus and P. aeruginosa, respectively. Prevalence of methicillin-resistant S. aureus (MRSA) was 49%. All S. aureus strains tested were susceptible to vancomycin and trimethoprim/sulfamethoxazole. Resistance to gentamycin, ciprofloxacin, amikacin, imipenem and ceftazidime among P. aeruginosa strains were the following: 96.4, 57.1, 53.6, 42.9, and 32.1%, respectively. Enteric bacteria remained fully susceptible (100%) to carbapenems only.

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