Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(4):313-324
Sarcoidosis – it is a systemic granulomatous disease, the cause and the factors leading to the disease progression are not known. The present literature review devoted to the presumptive factors that can be involved in the onset and progression of sarcoidosis such as mycobacteria, chlamydia, propionibacteria, viruses. The role of the above pathogens as a probable causative agents as well as triggers that can affect the immunological reactivity of macroorganism is discussed. As a possible triggers in the onset of sarcoidosis the use of antivirals and immunomodulators is mentioned.