The Anthrax

Clinical Microbiology and Antimicrobial Chemotherapy. 2002; 4(2):104-127

Journal article


Anthrax, along with smallpox and plague, is considered one of the most potential biological warfare agents. It has been proved during the recent bioterroristic events in the USA in the fall last year. This article presents the questions of etiology, epidemiology and pathogenesis of Bacillus anthracis infection. Clinical features of the different forms and major criteria for diagnosis of anthrax are described in details. Different microbiological diagnostics for confirmation of anthrax infection are analyzed. Management of the naturally occurring anthrax as well as patients with anthrax in mass casualty setting is emphasized. Routine preexposure and postexposure vaccination are also discussed. Recommendations for postexposure prophylaxis following an aerosol exposure to B.anthracis spores are presented.

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