Abstract
Diarrhea, which is associated with the usage of antimicrobials, is one of the important problems in clinical practice. This article reviews the questions of etiology, pathogenesis and epidemiology of antibiotic-associated diarrhea (AAD). Clinical forms and features of the AAD are discussed. Advantages and disadvantages of different microbiological diagnostics for Clostridium difficile infection, which is the most common cause of the AAD are also analyzed. The main approaches to the management of Clostridium difficile colitis, indications for use ofantibacterial therapy and problems of the choice of antimicrobials are presented.
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