Therapeutic Issues

Intravenous Immunoglobulins: Mechanisms of Action and Possible Clinical Applications

Clinical Microbiology and Antimicrobial Chemotherapy.2004; 6(3):273-281

Historically, intravenous immunoglobulins (ivIg) were initially used as replacement therapy in patients with antibody deficiency disorders.Later on ivIg were suggested to have advantages in treatment of patients with autoimmune and systemic …

Corticosteroids in the Treatment of Septic Shock: the History is Going on

Clinical Microbiology and Antimicrobial Chemotherapy. 2004; 6(2):133-142

Evidence-based analysis of clinical trials, concerning appropriateness of corticosteroids use and its efficacy in the treatment of septic shock, was performed. Results of pharmacoepidemiological study of corticosteroids use in Russian hospitals are …

Drug Therapy of Acute Otitis Media in Adult Outpatients: Results of the Multicenter Pharmacoepidemiological Study

Clinical Microbiology and Antimicrobial Chemotherapy. 2004; 6(2):124-132

Drug treatment of adult outpatients with acute otitis media (AOM) were analyzed. A total of 1489 case histo% ries of patients aged from 16 to 83 (55,6 ± 14,8) were included in the study from 8 Russian cities. The most frequently prescribed groups of …