Drug Therapy of Acute Otitis Media in Adult Outpatients: Results of the Multicenter Pharmacoepidemiological Study

Clinical Microbiology and Antimicrobial Chemotherapy. 2004; 6(2):124-132

Journal article


Drug treatment of adult outpatients with acute otitis media (AOM) were analyzed. A total of 1489 case histo% ries of patients aged from 16 to 83 (55,6 ± 14,8) were included in the study from 8 Russian cities. The most frequently prescribed groups of drugs were antimicrobials for systemic use (79,7%), otologicals (61,3%), antihistamines (44,1%), nasal preparations (37,5%), throat preparations (23,5%), and antimicrobials for local use (22,3%). The most common antimicrobials prescribed were аmpicillin (17,6%), doxycycline (16,7%), аmoxicillin (15,3%), and ciprofloxacin (10,4%). Mono% therapy with antimicrobials was used in 93,6% of cases, and their combinations in 6,4% of cases. Two courses of antimicrobial therapy were prescribed to 4,6% of patients. The study has shown significant shortcomings of cur% rent approaches to drug therapy for AOM: inappropriate choice of antimicrobials, the use of potentially toxic drugs, use of medications with unproven clinical efficacy.

0 Abstract
0 Crossref citations