Antimicrobial Resistance

This paper presents the study results of the representation relative level and drug resistance genes composition of intestinal microbiota in COPD patients with subsequent evaluation of the antibiotic therapy courses frequency effect on the risk of …

One of the main mechanisms of resistance of Gramnegative microorganisms to antibiotics is enzymatic hydrolysis by beta-lactamases (for example, metallobeta-lactamases). Searching of paths of strengthening of carbapenems action is possible due to …

Until now, mutational resistance to fluoroquinolones (FQs) that represent a second-line treatment option for chlamydial infections after macrolides and tetrxacyclines has not been described in clinical isolates of C. trachomatis. However, a …

In total 284 clinical nosocomial S. aureus strains isolated in 2011–2012 from patients hospitalized in 25 hospitals in 18 Russian cities were included in the study. Susceptibility to 19 antimicrobials was assessed by serial dilution method in …

Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 343 isolates of P. aeruginosa collected in 25 hospitals of 18 cities of Russia …

Acinetobacter baumannii and related species of the Acinetobacter calcoaceticus-baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 252 …

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 573 isolates of Enterobacteriaceae collected in 25 hospitals of 18 cities of …

Streptococcus pneumoniae strains isolated from children of Krasnoyarsk (Siberia, Russian Federation) were examined. Authors determined Streptococcus pneumoniae serotypes and antimicrobial resistance. 16.7% of strains were multiple resistant with high …

Acquired bacterial resistance is currently one of the causes of mortality and morbidity from infectious diseases. Mathematical modeling allows us to predict the further spread of resistance and to some extent to control its dynamics. The purpose of …

Objective. To study antimicrobial resistance of Haemophilus influenzae and its trends in different Russian regions over the period of 2004–2009. Materials and Methods. This study included consecutive clinical strains of H. influenzae obtained from patients with different infections (pneumonia, acute otitis media, meningitis, bacteremia, COPD exacerbation, etc.) in Central, Volga, Ural, and Siberian federal districts of Russia over the period of 2004–2009. Susceptibility to 12 antimicrobial agents was determined by broth microdilution method according to the Clinical Laboratory Standards Institute guidelines (CLSI 2013).