Antimicrobial Resistance | CMAC

Antimicrobial Resistance

Carbapenemase-producing Gram-negative bacteria in the Russian research center of radiology and surgical technologies

Objective. To assess an incidence rate of carbapenemase-producing Gram-negative bacteria isolated from patients in the RRCRST. Materials and Methods. The clinical Gram-negative isolates obtained from patients hospitalized to the RRCRST over the period of February 2014 to April 2016 were tested. A screening for carbapenem resistance was performed by culture on chromogenic media, and species identification was made using MALDI-TOF massspectrometry. Susceptibility of Gram-negative bacteria to antimicrobial agents was determined using VITEK-2.

Antimicrobial resistance of Neisseria gonorrhoeae in the Russian Federation: regional differences

Objective. To assess regional differences in antimicrobial susceptibility of N. gonorrhoeae in the Russian Federation. Materials and Methods. A total of 365 N. gonorrhoeae strains were isolated over the period of 2015-2016 in Arkhangelsk, Astrakhan, Bryansk, Kaluga, Novosibirsk, Omsk, Ryazan, Tomsk regions, Republic of Tatarstan and Chuvashiya Republic. Antimicrobial susceptibility testing was performed by agar dilution method and assessed according to MUK 4.2.1890-04 criteria using WHONET software (v5.4). Molecular typing was performed according to the NG-MAST protocol.

Antimicrobial resistance and clonal evolution of Streptococcus pneumoniae serotype 19A in Russia during 2002-2013

After the introduction of the conjugated 7-valent pneumococcal vaccine (PCV7) the incidence of infections, caused by non-vaccine serotypes of S. pneumoniae, especially by 19А serotype, significantly increased. But in few countries similar phenomenon …

Prevalence of carbapenemase-producing Klebsiella pneumoniae isolates in Belarus and their competitive ability

Susceptibility to antibiotics was determined for 208 hospital isolates from 4 regions of Belarus. The broad abundance of resistance to carbapenems was shown. The genes of carbapenemases blaNDM, blaOXA-48 and blaKPC were detected in 55 strains from 12 …

Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities. …

Antimicrobial resistance of nosocomial Enterobacteriaceae isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 1670 isolates of Enterobacteriaceae collected in 35 hospitals of 22 cities of …

Antimicrobial resistance of nosocomial Acinetobacter spp. isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Acinetobacter baumannii and related species of the A. baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 568 isolates of Acinetobacter …

Antimicrobial resistance of nosocomial Pseudomonas aeruginosa isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014

Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 743 isolates of P. aeruginosa collected in 63 hospitals of 22 cities of Russia …

Antimicrobial Susceptibility of Helicobacter pylori Isolates from Patients with Gastric Cancer and Precancer

colonization of gastric mucosa with Helicobacter pylori in patients with precancerous conditions (adenomatous polyp, hyperplastic polyp, focal hypertrophy, erosions) and gastric cancer (adenocarcinoma, signet ring cell carcinoma, carcinoid). The …

Current Trends in Antimicrobial Resistance of Neisseria gonorrhoeae in Russian Federation

Objective. of current Neisseria gonorrhoeae isolates and determine its trends over the RU-GASP (Russian Gonococcal Antimicrobial Susceptibility Programme) period. Materials and Methods. A total of 293 strains of N. gonorrhoeae isolated in 11 regions within Central, North-Western, Volga, Southern, and Siberian federal districts over the 2015–2016 were included in this study. Susceptibility to benzylpenicillin, ceftriaxone, tetracycline, spectinomycin, azithromycin, and ciprofloxacin was determined by agar dilution method and assessed according to the CLSI, EUCAST and MUK 4.