Antimicrobial Resistance

Objective. Objectives. To research the qualitative relationships between the level of antimicrobial resistance and the level of consumption of different antimicrobial agents, and to further apply this knowledge to minimize the level of resistance. Materials and Methods. An extensive simulation was performed based on the previously implemented model describing the relationship between a resistance and levels of antibiotic consumption. It makes possible to estimate the resistance growth rates in different antibiotic consumption strategies.

Pseudomonas aeruginosa is a dangerous opportunistic pathogen. One of the most negative clinically significant features of P. aeruginosa is associated with the rapid acquisition of antimicrobial resistance. This review provides an analysis of current …

Mycoplasma pneumoniae is a bacterial pathogen cause of upper and lower respiratory tract infections, transmitted by airborne droplets, causing outbreaks of pneumonia mainly in closed groups. According with recommendations, M. pneumoniae infections …

This study analyzed a prevalence of carbapenem-resistant Klebsiella pneumoniae strains obtained in the Privolzhsky Federal Medical Research Center units and their antibiotic resistance mechanisms. During the study year, the incidence of K. pneumoniae …

Objective. To assess an incidence rate of carbapenemase-producing Gram-negative bacteria isolated from patients in the RRCRST. Materials and Methods. The clinical Gram-negative isolates obtained from patients hospitalized to the RRCRST over the period of February 2014 to April 2016 were tested. A screening for carbapenem resistance was performed by culture on chromogenic media, and species identification was made using MALDI-TOF massspectrometry. Susceptibility of Gram-negative bacteria to antimicrobial agents was determined using VITEK-2.

Objective. To assess regional differences in antimicrobial susceptibility of N. gonorrhoeae in the Russian Federation. Materials and Methods. A total of 365 N. gonorrhoeae strains were isolated over the period of 2015-2016 in Arkhangelsk, Astrakhan, Bryansk, Kaluga, Novosibirsk, Omsk, Ryazan, Tomsk regions, Republic of Tatarstan and Chuvashiya Republic. Antimicrobial susceptibility testing was performed by agar dilution method and assessed according to MUK 4.2.1890-04 criteria using WHONET software (v5.4). Molecular typing was performed according to the NG-MAST protocol.

After the introduction of the conjugated 7-valent pneumococcal vaccine (PCV7) the incidence of infections, caused by non-vaccine serotypes of S. pneumoniae, especially by 19А serotype, significantly increased. But in few countries similar phenomenon …

Susceptibility to antibiotics was determined for 208 hospital isolates from 4 regions of Belarus. The broad abundance of resistance to carbapenems was shown. The genes of carbapenemases blaNDM, blaOXA-48 and blaKPC were detected in 55 strains from 12 …

The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities. …

Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 1670 isolates of Enterobacteriaceae collected in 35 hospitals of 22 cities of …