Antimicrobial Resistance | CMAC

Antimicrobial Resistance

Current State of Antibiotic Resistance of Pathogens Causing Community-Acquired Urinary Tract Infections in Russia: «DARMIS» Study (2010–2011)

Objective. Objectives. To investigate etiology and susceptibility of pathogens causing community-acquired urinary tract infections (UTIs) in different regions of Russia in various patients’ subsets to the most clinically used antimicrobials. Materials and Methods. A total of 903 uropathogens isolated from urine samples of children and adults of all age groups with acute (and recurrence of chronic) community-acquired UTIs, including pregnant women with asymptomatic bacteriuria were collected in 26 centers of 18 cities in Russia during 2010–2011 and included in the «DARMIS» study.

Antimicrobial Susceptibility of Bacterial Strains Contained in the Probiotic Preparation «Linex»

Currently, there is an ever-increasing consumption of probiotics contained in foods, food supplements, and medicinal products. A number of studies to determine efficacy of those products in different medical conditions is also increasing. Meanwhile, …

Independent Acquisition of Quinolone Resistance in Clonally Related Nosocomial Strains of Salmonella Typhimurium Due to Hypermutability

Here we report on a high incidence of quinolone resistance (43,1%) among nosocomial CTX-M-5 ESBLproducing S. Typhimurium isolates belonging to a single clonal group isolated in Russia, Belarus, and Kazakhstan. The resistance mechanism in all cases …

Prevalence and Molecular Epidemiology of Gram-negative Bacteria Producing Metallo-β-lactamases (MBLs) in Russia, Belarus and Kazakhstan

The prevalence and molecular epidemiology of MBLproducing Gram-negative bacteria have been studied in Russia (1998–2010), Belarus and Kazakhstan (2005– 2010). Analysis of nosocomial strains isolated as part of several multicentre surveillance studies …

Antimicrobial Resistance of Bacteria in Biofilms

Different mechanisms of antimicrobial resistance development in biofilm bacteria are reviewed in the article. Practical approaches to the susceptibility testing of bacteria in biofilms are analyzed.

Clonal dissemination of CTX-M-5-producing nosocomial strains of Salmonella Typhimurium in Russia, Belarus, and Kazakhstan

In this paper, the evidence of broad geographic dissemination of Salmonella enterica serovar Typhimurium strains belonging to a single genetic lineage is presented. The isolates described possess resistance to oxiiminocephalosporines due to …

Identification of a Novel MRSA ST239 Strain Producing Toxic Shock Syndrome Toxin (TSST-1) in a HIV-infected Patient with Pneumonia

Methicillin-resistant Staphylococcus aureus (MRSA) ST239 is one of the most common nosocomial genotypes worldwide. Typical MRSA ST239 strains do not produce toxic shock syndrome toxin-1 (TSST-1), which is encoded by tst gene at staphylococcal …

Phenotypic and Genotypic Characteristics of Pneumococci Isolated from Patients with Pneumococcal Meningitis

Antimicrobial susceptibility, serotype distribution, and multilocus sequence types of Streptococcus pneumoniae isolated from the patients with meningitis were determined. We tested a total of 84 isolates which have been obtained in Moscow during …

Serological Characteristics and Antimicrobial Susceptibility of Streptococcus pneumoniae Isolated from Children 0–5 Years of Age in Different Regions of Russia

This article presents results of the study on serotypes distribution of clinical and colonized strains of S. pneumoniae circulated in different regions of Russian Federation in children attended day-care centers and orphanages, and in pediatric …

Antimicrobial Resistance of Gram-negative Bacteria Isolated from Biopsy Samples in Patients with Ulcerative Colitis

Objective. To investigate spectrum and antimicrobial susceptibility of colonic microorganisms isolated from biopsy samples in patients with ulcerative colitis. Materials and Methods. A total of 34 patients with ulcerative colitis (19 to 75 years of age) treated in proctology unit (Surgery Clinic of Samara State Medical University) during the 2009–2010 were examined in this study. Results. A total of 70 gram-negative isolates were obtained, of which Enterobacteriaceae were the most predominant pathogens.