Аннотация
При наличии весомых теоретических преимуществ, методика введения антибактериальных препаратов в дыхательные пути с целью лечения острой пневмонии всё ещё не нашла широкого применения в клинической практике. Ограничением на пути внедрения методики служит не только недостаток достоверных клинических данных, подтверждающих результативность такой терапии, но и сомнения относительно эффективности доставки антибиотика в очаг инфекции. В статье представлен обзор способов повышения эффективности противомикробной терапии при введении антибиотиков в дыхательные пути. В частности, обсуждается использование экзогенного лёгочного сурфактанта как перспективного средства доставки эндотрахеально введенных противомикробных препаратов.
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