Профилактика инфекционных осложнений в травматологии и ортопедии | КМАХ

Профилактика инфекционных осложнений в травматологии и ортопедии

Клиническая Микробиология и Антимикробная Химиотерапия. 2014; 16(3):168-175

​ Хвостов Д.Л., Привольнев В.В.
антибиотикопрофилактика травматология ортопедия имплант
Раздел
Рекомендации
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2014; 16(3):168-175

Аннотация

Публикация содержит обзор рекомендаций по антибиотикопрофилактике в травматологии и ортопедии. Современная ортопедия включает использование разнообразных внутрикостных и внешних металлических конструкций, замену целых сегментов конечности и суставов и предполагает использование пациентом крупных имплантов в течение многих лет жизни. Всё это изменило характер послеоперационных инфекционных осложнений и повлекло за собой пересмотр рекомендаций по антибиотикопрофилактике. Рост числа поздних инфекционных осложнений, изменение микробной этиологии инфекций области хирургического вмешательства, необходимость удаления или замещения металлических конструкций, значительная хирургическая агрессия при повторных вмешательствах связанная с этим, внесли существенные изменения в стратегию антибиотикопрофилактики в травматологии и ортопедии.

  • 1. Kaiser A.B. Antimicrobial prophylaxis in surgery. N Engl J Med 1986; 315:1129–38.
  • 2. Elek S.D., Conen P.E. Trie-virulence of Staphylococcus pyrogenes for infection. Br J Exp Pathol 1957; 38:573-86.
  • 3. Zimmerli W., Lew P.D., Waldvogel F.A. Pathogenesis of foreign body infection. Evidence for a local granulocyte defect. J Clin Invest 1994; 73:1191-1200.
  • 4. Zimmerli W., Waldvogel F.A., Vaudaux P., et al. Pathogenesis of foreign body infection: description and characteristics of an animal model. J Infect Dis 1995; 146:487-97.
  • 5. Gristina A.G., Shibata Y., Giridhar G., et al. The glycocalyx, biofilm, microbes, and resistant infection. Semin Arthroplasty 1994; 5:160-70.
  • 6. Gristina A.G. Implant failure and the immuno-incompetent fibro-inflammatory zone. Clin Orthop Relat Res 1994; 298:106-18.
  • 7. Gristina A.G., Costerton J.W. Bacterial adherence to biomaterials and tissue. The significance of its role in clinical sepsis. J Bone Joint Surg Am 1985; 67:264-73.
  • 8. Ainscow D.A., Denham R.A. The risk of haematogenous infection in total joint replacements. J Bone Joint Surg 1984; 66:580-2.
  • 9. Curry S., Phillips H. Joint arthroplasty, dental treatment, and antibiotics: a review. J Arthroplasty 2002; 17:111-3.
  • 10. Dellinger E.P., Gross P.A., Barrett T.L., et al. Quality standard for antimicrobial prophylaxis in surgical procedures. The Infectious Diseases Society of America. Infect Control Hasp Epidemiol 1994; 15:182-8.
  • 11. Gustilo R.B., Mendoza R.M., Williams D.N. Problems in the management of type П1 (severe) open fractures: a new classification of type III open fractures. J Trauma 1994; 24:742-6.
  • 12. Periti P., Mini E., Mosconi G. Antimicrobial prophylaxis in orthopaedic surgery: the role of teicoplanin. J Antimicrob Chemother 1998; 41:329-40.
  • 13. Strausbaugh L.J., Crossley K.B., Nurse B.A., Thrupp L.D. Antimicrobial resistance in long-term-care facilities. Infect Control Hosp Epidemiol 1996; 17:129-40.
  • 14. Mauerhan D.R., Nelson C.L., Smith D.L., et al. Prophylaxis against infection in total joint arthroplasty. One day of cefuroxime compared with three days of cefazolin. J Bone Joint Surg Am 1994; 76:39-45.
  • 15. Page C.P., Bohnen J.M., Fletcher J.R., et al. Antimicrobial prophylaxis for surgical wounds. Guidelines for clinical care. Arch Surg 1993; 128:79-88.
  • 16. Patzakis M.J., Wilkins J., Kumar J., et al. Comparison of the results of bacterial cultures from multiple sites in chronic osteomyelitis of long bones. A prospective study. J Bone Joint Surg Am 1994; 76:664-6.
  • 17. Greene C., McDevitt D., Francois P., et al. Adhesion properties of mutants of Staphylococcus aureus defective in fibronectin-binding proteins and studies on the expression of fnb genes. Mol Microbiol 1995; 17:1143-52.
  • 18. Steckelberg J.M., Osmon D.R. Infections associated with indwelling medical devices. In: Bisno A.L., Waldvogel F.A., editors. Prosthetic joint infections. Washington DC: ASM Press: 1994; 259-901.
  • 19. Boxma H., Broekhuizen T., Patka P., et al. Randomised controlled trial of single-dose antibiotic prophylaxis in surgical treatment of closed fractures: the Dutch Trauma Trial. Lancet 1996; 347:133-7.
  • 20. Pavel A., Smith R.L., Ballard A., et al. Prophylactic antibiotics in clean orthopedic surgery. J Bone Joint Surg 1974; 56:777-82.
  • 21. Prokuski L. Prophylactic antibiotics in orthopaedic surgery. J Am Acad Orthop Surg 2008; 16:283-93.
  • 22. Zgonis T., Jolly G.P., Garbalosa J.C. The efficacy of prophylactic intravenous antibiotics in elective foot and ankle surgery. J Foot Ankle Surg 2004; 43:97-103.
  • 23. Antimicrobial prophylaxis for surgery. Treat Guidel Med Lett 2009; 7:47-52.
  • 24. Kurzweil P.R. Antibiotic prophylaxis for arthroscopic surgery. Arthroscopy 2006; 22:452-4.
  • 25. Wieck J.A., Jackson J.K., O’Brien T.J., et al. Efficacy of prophylactic antibiotics in arthroscopic surgery. Orthopedics 1997; 20:133-4.
  • 26. Bert J.M., Giannini D., Nace L. Antibiotic prophylaxis for arthroscopy of the knee: is it necessary? Arthroscopy 2007; 23:4-6.
  • 27. Babcock H.M., Carroll C., Matava M., et al. Surgical site infections after arthroscopy: outbreak investigation and case control study. Arthroscopy 2003; 19:172-81.
  • 28. Olix M.L., Klug T.J., Coleman C.R., et al. Prophylactic antibiotics in elective operations on bones, joints, and tendons. Surg Forum 1960; 10:818-9.
  • 29. Tachdjian M.O., Compere E.L. Postoperative wound infections in orthopedic surgery: evaluation and prophylactic antibiotics. J Int Coll Surg 1957; 28:797-805.
  • 30. Boyd R.J., Burke J.F., Colton T. A doubleblind clinical trial of prophylactic antibiotics in hip fractures. J Bone Joint Surg 1973; 55:1251-8.
  • 31. Boxma H., Broekhuizen T., Patka P., et al. Randomised controlled trial of single-dose antibiotic prophylaxis in surgical treatment of closed fractures: the Dutch Trauma Trial. Lancet 1996; 347:1133-7.
  • 32. Fitzgerald R.H. Infections of hip prosthesis and artificial joints. Infect Dis Clin North Am 1989; 3:329-38.
  • 33. Southwell-Keely J.P., Russo R.R., App B., et al. Antibiotic prophylaxis in hip fracture surgery: a meta-analysis. Clin Orthop Relat Res 2004; 410:179-84.
  • 34. Gillespie W.J., Walenkamp G. Antibiotic prophylaxis for surgery for proximal femoral and other closed long bone fractures. Cochrane Database Syst Rev 2001; 1:CD000244.
  • 35. Hahnel J., Burdekin H., Anand S. Readmissions following hip fracture surgery. Ann R Coll Surg Engl 2009; 91:591-5.
  • 36. Gulihar A., Nixon M., Jenkins D., et al. Clostridium difficile in hip fracture patients: prevention, treatment and associated mortality. Injury 2009; 40:746-51.
  • 37. Cunha B.A., Gossling H.R., Pasternak H.S., et al. The penetration characteristics of cefazolin, cephalothin, and cephradine into bone in patients undergoing total hip replacement. J Bone Joint Surg 1977; 59:856-9.
  • 38. Mangram A.J., Horan T.C., Pearson M.L., et al. Guideline for prevention of surgical site infection. Infect Control Hosp Epidemiol 1999; 20:250-78.
  • 39. Starks I., Ayub G., Walley G., et al. Singledose cefuroxime with gentamicin reduces Clostridium difficile-associated disease in hip-fracture patients. J Hosp Infect 2008; 70:21-6.
  • 40. Barker F.G. Efficacy of prophylactic antibiotic therapy in spinal surgery: a meta-analysis. Neurosurgery 2002; 51:391-401.
  • 41. Bratzler D.W., Houck P.M., for the Surgical Infection Prevention Guidelines Writers Workgroup. Antimicrobial prophylaxis for surgery: an advisory statement from the national surgical infection prevention project. Clin Infect Dis 2004; 38:1706-15.
  • 42. Kalmeijer M.D., Coertjens H., Van NieuwlandBollen P.M., et al. Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo-controlled study. Clin Infect Dis 2002; 35:353-8.
  • 43. Kallen A.J., Wilson C.T., Larson R.J. Perioperative intranasal mupirocin for the prevention of surgical-site infections: systematic review of the literature and metaanalysis. Infect Control Hosp Epidemiol 2005; 26:916-22.
  • 44. Trampuz A., Zimmerli W. Antimicrobial agents in orthopedic surgery: prophylaxis and treatment. Drugs 2006; 66:1089-105.
  • 45. Gernaat-Van Der Sluis A.J., Hoogenboom-Verdegaal A.M., Edixhoven P.J., et al. Prophylactic mupirocin could reduce orthopedic wound infections: 1044 patients treated with mupirocin compared with 1260 historical controls. Acta Orthop Scand 1998; 69:412-4.
  • 46. Wilcox M.H., Hall J., Pike H., et al. Use of perioperative mupirocin to prevent methicillin resistant Staphylococcus aureus (MRSA) orthopedic surgical site infections. J Hosp Infect 2003; 54:196-201.
  • 47. Coskun D., Aytac J. Decrease in Staphylococcus aureus surgical-site infection rates after orthopaedic surgery after intranasal mupirocin ointment. J Hosp Infect 2004; 58:90-1.
  • 48. Van Rijen M.M., Bonten M., Wenzel R.P., et al. Intranasal mupirocin for reduction of Staphylococcus aureus infections in surgical patients with nasal carriage: a systematic review. J Antimicrob Chemother 2008; 61:254-61.
  • 49. Hacek D.M., Robb W.J., Paule S.M., et al. Staphylococcus aureus nasal decolonization in joint replacement surgery reduces infection. Clin Orthop Relat Res 2008; 466:1349- 55.
  • 50. Rao N., Cannella B., Crossett L.S., et al. A preoperative decolonization protocol for Staphylococcus aureus prevents orthopaedic infections. Clin Orthop Relat Res 2008; 466:1343-8.
  • 51. Kim D.H., Spencer M., Davidson S.M., et al. Institutional prescreening for detection and eradication of methicillinresistant Staphylococcus aureus in patients undergoing elective orthopaedic surgery. J Bone Joint Surg Am 2010; 92:1820-6.
  • 52. Bohsali K.I., Wirth M.A., Rockwood C.A. Complications of total shoulder arthroplasty. J Bone Joint Surg Am 2006; 88:2279-92.
  • 53. Glazebrook M.A., Arsenault K., Dunbar M. Evidencebased classification of complications in total ankle arthroplasty. Foot Ankle Int 2009; 30:945-9.
  • 54. Gougoulias N., Khanna A., Maffulli N. How successful are current ankle replacements? A systematic review of the literature. Clin Orthop Relat Res 2010; 468:199-208.
  • 55. Blom A.W., Brown J., Taylor A.H., et al. Infection after total knee arthroplasty. J Bone Joint Surg Br 2004; 86:688-91.
  • 56. Kasten M.D., Skinner H.B. Total elbow arthroplasty. An 18-year experience. Clin Orthop Relat Res 1993; 290:177-88.
  • 57. Edwards J.R., Peterson K.D., Mu Y., et al. National Healthcare Safety Network (NHSN) report: data summary for 2006 through 2008. Am J Infect Control 2009; 37:783-805.
  • 58. Ericson C., Lidgren L., Lindberg L. Cloxacillin in the prophylaxis of postoperative infections of the hip. J Bone Joint Surg 1973; 55:808-13.
  • 59. Periti P., Stringa G., Mini E., et al. Comparative multicenter trial of teicoplanin versus cefazolin for antimicrobial prophylaxis in prosthetic joint implant surgery. Eur J Clin Microbiol Infect Dis 1999; 18:113-9.
  • 60. Minnema B., Vearncombe M., Augustin A., et al. Risk factors for surgical-site infection following primary total knee arthroplasty. Infect Control Hosp Epidemiol 2004; 25:477-80.
  • 61. Matthews P.C., Berendt A.R., McNally M.A., et al. Diagnosis and management of prosthetic joint infection. BMJ 2009; 338:1378-83.
  • 62. Blom A.,W, Taylor A.H., Pattison G., et al. Infection after total hip arthroplasty. J Bone Joint Surg Br 2003; 85:956-9.
  • 63. Albuhairan B., Hind D., Hutchinson A. Antibiotic prophylaxis for wound infections in total joint arthroplasty. J Bone Joint Surg Br 2008; 90:915-9.
  • 64. Fish D.N., Hoffman H.M., Danziger L.H. Antibiotic impregnated cement use in U.S. hospitals. Am J Hosp Pharm 1992; 49:2469-74.
  • 65. Malik M.H., Gambhir A.K., Bale L., et al. Primary total hip replacement: a comparison of a nationally agreed guide to practice and current surgical technique as determined by the North West Regional Arthroplasty Registry. Ann R Coll Surg Engl 2004; 86:113-8.
  • 66. Bourne R.B. Prophylactic use of antibiotic bone cement: an emerging standard - in the affirmative. J Arthroplasty 2004; 19(suppl 1):69-72.
  • 67. Engesaeter L.B., Lie S.A., Espehaug B., et al. Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0 to 14 years in the Norwegian Arthroplasty Register. Acta Orthop Scand 2003; 74:644-51.
  • 68. Espehaug B., Engesaeter L.B., Vollset S.E., et al. Antibiotic prophylaxis in total hip arthroplasty: review of 10,905 primary cemented total hip replacements reported to the Norwegian Arthroplasty Register, 1987 to 1995. J Bone Joint Surg Br 1997; 79:590-5.
  • 69. Jiranek W.A., Hanssen A.D., Greenwald A.S. Antibioticloaded bone cement for infection prophylaxis in total joint replacement. J Bone Joint Surg 2006; 88:2487-500.
  • 70. McQueen M.M., Hughes S.P., May P., et al. Cefuroxime in total joint arthroplasty. Intravenous or in bone cement. J Arthroplasty 1990; 5:169-72.
  • 71. Josefsson G., Kolmert L. Prophylaxis with systematic antibiotics versus gentamicin bone cement in total hip arthroplasty. A ten-year survey of 1,688 hips. Clin Orthop Relat Res 1993; 292:210-4.
  • 72. Hanssen A.D., Osmon D.R. The use of prophylactic antimicrobial agents during and after hip arthroplasty. Clin Orthop Relat Res 1999; 369:124-38.
  • 73. Jiranek W. Antibiotic-loaded cement in total hip replacement: current indications, efficacy, and complications. Orthopedics 2005; 28(suppl):s873-7.
  • 74. Diefenbeck M., Mückley T., Hofman G.O. Prophylaxis and treatment of implant-related infections by local application of antibiotics. Injury 2006; 37(suppl 2):S95-104.
  • 75. Hanssen A.D. Prophylactic use of antibiotic bone cement: an emerging standard - in opposition. J Arthroplasty 2004; 19(suppl 1):73-7.
  • 76. Korinek A.M., Golmard J.L., Elcheick A., et al. Risk factors for neurosurgical site infections after craniotomy: a critical reappraisal of antibiotic prophylaxis on 4578 patients. Br J Neurosurg 2005; 19:155-62.
  • 77. Brown E.M., Path F.R., Pople I.K., et al. Prevention of postoperative infection in patients undergoing spinal surgery. Spine 2004; 29:938-45.
  • 78. American Academy of Orthopaedic Surgeons. Information statement: the use of prophylactic antibiotics in orthopaedic medicine and the emergence of vancomycinresistant bacteria. www.aaos.org/about/papers/advistmt/1016.asp (accessed 2008 May 13).
  • 79. Van Kasteren M.E., Mannien J., Ott A., et al. Antibiotic prophylaxis and the risk of surgical site infections following total hip arthroplasty: timely administration is the most important factor. Clin Infect Dis 2007; 44:921-7.
  • 80. American Academy of Orthopaedic Surgeons. Information statement: recommendations for the use of intravenous antibiotic prophylaxis in primary total joint arthroplasty. www.aaos.org/about/papers/advistmt/1027.asp (accessed 2008 May 13).
  • 81. Jaeger M., Maier D., Kern W.V., et al. Antibiotics in trauma and orthopedic surgery - a primer of evidencebased recommendations. Injury 2006; 37:s74-80.
  • 82. Ericson C., Lidgren L., Lindberg L. Cloxacillin in the prophylaxis of postoperative infections of the hip. J Bone Joint Surg 1973; 55:808-13.
  • 83. Pollard J.P., Hughes S.P., Scott J.E., et al. Antibiotic prophylaxis in total hip replacement. Br Med J 1979; 1:707-9.
  • 84. Burnett J.W., Gustilo R.B., Williams D.N., et al. Prophylactic antibiotics in hip fractures. J Bone Joint Surg 1980; 62:457-62.
  • 85. Tengve B., Kjellander J. Antibiotic prophylaxis in operations on trochanteric femoral fractures. J Bone Joint Surg1978; 60:97-9.
  • 86. Nelson C.L., Green T.G., Porter R.A., et al. One day versus seven days of preventive antibiotic therapy in orthopedic surgery. Clin Orthop Relat Res 1983; 176:258-63.
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