Аннотация
Азитромицин и кларитромицин занимают важное место в лечении внебольничных бактериальных инфекций. Они активны в отношении актуальных возбудителей инфекций дыхательных путей, ЛОР-органов, инфекций передаваемых половым путём, воспалительных заболеваний органов малого таза, инфекции H. pylori, нетуберкулёзных микобактерий. Это позволяет использовать «новые макролиды» в качестве лекарственных средств первого выбора при лечении данных инфекций в качестве монотерапии или в сочетании с бета-лактамными антибиотиками. Современные макролиды обладают важными иммуномодулирующими и противовоспалительными свойствами и характеризуются благоприятным профилем безопасности. Нежелательные явления при применении макролидов в подавляющем большинстве случаев представляют собой функциональные изменения со стороны различных органов и систем, являются обратимыми и проходят после завершения лечения макролидами.
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