Аннотация
Инвазивные микозы у пациентов с тяжелыми заболеваниями, находящихся в ОРИТ, у онкогематологических пациентов и пациентов после трансплантации внутренних органов являются очень важной мишенью для применения адекватной профилактической, эмпирической и превентивной противогрибковой терапии. Это обусловлено не только высокой частотой встречаемости инвазивных микозов в данной популяции пациентов, но и высокими показателями смертности и материальными затратами на ведение таких больных. Безусловно, максимально ранняя постановка диагноза обеспечивает наиболее оптимальный прогноз у данной группы больных. В настоящее время имеется достаточное количество антимикотиков для системного применения, что позволяет сделать адекватный выбор терапии у конкретного пациента в зависимости от клинического сценария, наличия тех или иных факторов риска, эпидемиологических данных относительно потенциальных возбудителей, а также исходя из клинической фармакологии препарата. В обзоре представлена информация о профилактической, превентивной и эмпирической терапии инвазивных микозов у разных категорий пациентов, а также затронуты некоторые аспекты диагностики инвазивных грибковых инфекций.
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