Роль Helicobacter pylori в патологии человека

Клиническая Микробиология и Антимикробная Химиотерапия. 2002; 4(2):128-145

​ Шкитин В.А., Шпирна А.И., Старовойтов Г.Н.
Helicobacter pylori микробиология патогенность иммунитет хронический гастрит язвенная болезнь аденокарцинома желудка
Раздел
Болезни и возбудители
Тип
Журнальная статья
Публикация
Клиническая Микробиология и Антимикробная Химиотерапия. 2002; 4(2):128-145

Аннотация

Инфекция, вызванная Helicobacter pylori, занимает одно из первых мест в мире по распространенности. К H.pylori-ассоциированным болезням относятся хронический гастрит, язвенная болезнь желудка и двенадцатиперстной кишки. Не исключается роль этого микроорганизма в развитии MALT-лимфомы и аденокарциномы желудка. В данной статье представлены микробиологическая характеристика H.pylori, характер и особенности взаимоотношений его с макроорганизмом, молекулярные основы патогенности. Большое внимание уделено особенностям формирования иммунитета при H. рylori-инфекции. Обсуждаются механизмы участия микроорганизма в формировании язвы желудка и двенадцатиперстной кишки. Приведен обзор данных, касающихся роли H.pylori как фактора риска в развитии онкологических заболеваний желудка.

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