Аннотация
Streptococcus pneumoniae является одним из основных возбудителей менингита, среднего отита, синусита, внебольничной пневмонии в различных возрастных группах населения. Особую проблему представляет рост числа антиботикорезистентных штаммов пневмококка, выделяемых при различных нозологических формах, что приводит к значительному увеличению затрат на лечение таких пациентов. Наряду с использованием эффективных антимикробных препаратов существует возможность проведения специфической профилактики пневмококковых инфекций у взрослых и детей. Зарегистрированная в Российской Федерации 23-валентная пневмококковая полисахаридная вакцина является эффективной и безопасной у лиц в возрасте >2 лет. Однако данная вакцина не обеспечивает достаточной защиты детей в возрасте Ј2 лет. В то же время зарегистрированная в 2000 г. в США и некоторых странах Западной Европы конъюгированная 7-валентная вакцина показала свою эффективность у детей в возрасте Ј2 лет, что открывает широкие перспективы для профилактики пневмококковых инфекций. В данном обзоре представлены современные рекомендации по применению пневмококковых вакцин с позиций доказательной медицины и рассмотрены перспективы вакцинации.
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